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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NamePlatelet-activating factor receptor
SpeciesMus musculus (Mouse)
GenePtafr
SynonymAGEPC receptor
PAF receptor
PAF-R
PAFr
DiseaseN/A for non-human GPCRs
Length341
Amino acid sequenceMEHNGSFRVDSEFRYTLFPIVYSVIFILGVVANGYVLWVFANLYPSKKLNEIKIFMVNLTMADLLFLITLPLWIVYYYNEGDWILPNFLCNVAGCLFFINTYCSVAFLGVITYNRYQAVAYPIKTAQATTRKRGISLSLIIWVSIVATASYFLATDSTNLVPNKDGSGNITRCFEHYEPYSVPILVVHVFIAFCFFLVFFLIFYCNLVIIHTLLTQPMRQQRKAGVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFRKHLSEKFYSMRSSRKCSRATSDTCTEVIVPANQTPIVSLKN
UniProtQ62035
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3993
IUPHAR334
DrugBankN/A

Known ligands

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Total entries: 233
Page:  / 3 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
33712D structureCID 15005336C32H30ClN5O3568.0746 / 25.6No
42512D structure2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-1,4-dihydro-5H-1-benzazepin-5-oneC23H18N4O366.4244 / 13.9Yes
43422D structureCHEMBL101957C28H30N4O438.5754 / 13.5Yes
54152D structureCHEMBL418989C28H31N5O3S517.6487 / 02.9No
79282D structure2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(2-chloro-3-pyridinyl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl esterC33H28ClN7O3606.0838 / 24.8No
5532922D structure7-epi-ginkgolide CC20H24O11440.40111 / 4-1.4No
5532932D structureGinkgolide CC20H24O11440.40111 / 4-1.4No
122432D structureCID 15005338C33H29ClN4O3565.076 / 26.0No
148642D structureCHEMBL318908C27H27N5O2453.5466 / 04.0Yes
181392D structureCHEMBL103571C28H29N5O2467.5735 / 03.1Yes
267332D structureCHEMBL103903C27H26N4O422.5324 / 04.3Yes
271582D structureCHEMBL545072C27H30ClN5O476.0215 / 1N/AN/A
317972D structureCHEMBL103561C28H31N5O453.595 / 13.3Yes
336602D structureCHEMBL102070C27H28N6O2468.5616 / 11.7Yes
349632D structureCHEMBL102918C28H29N5O2467.5735 / 12.8Yes
363812D structureCHEMBL1203313C22H28ClN5O413.955 / 2N/AN/A
379742D structureCHEMBL542731C26H29ClN4432.9964 / 1N/AN/A
402432D structureCHEMBL318163C24H27N5O3433.5126 / 01.5Yes
409332D structureCHEMBL320900C33H28ClN5O3S610.1297 / 27.1No
413042D structureCHEMBL555567C26H30ClN5448.0115 / 2N/AN/A
491112D structureCHEMBL133120C25H25N3O3415.4933 / 01.9Yes
502172D structureCHEMBL154459C34H53IN2O3664.7134 / 0N/ANo
520052D structureCHEMBL3216197C26H28Cl2N4O483.4374 / 2N/AN/A
557742D structureCHEMBL340544C26H25N3O395.5063 / 04.1Yes
576212D structureCHEMBL422160C31H47IN2O4638.6315 / 0N/ANo
610712D structureCHEMBL103694C29H34N4O2470.6175 / 04.2Yes
614112D structureCHEMBL100190C25H29N5O2431.545 / 01.4Yes
618502D structureCHEMBL103636C22H23F3N4O416.4487 / 03.1Yes
646062D structureCHEMBL350961C39H40ClN7O3S722.30510 / 06.8No
668312D structureCHEMBL322184C26H27N5O425.5365 / 12.7Yes
705772D structure2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(3-pyridinyl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl esterC33H29N7O3571.6418 / 23.9No
711922D structureCHEMBL335853C25H24N4S412.5554 / 03.8Yes
717062D structureCHEMBL131597C25H25N5O411.5094 / 13.0Yes
722422D structureCHEMBL423711C28H26N4O434.5434 / 04.1Yes
740172D structureCHEMBL408135C39H38ClN7O4S736.28810 / 06.4No
746832D structureCHEMBL3216401C27H30Cl2N4O497.4644 / 2N/AN/A
749142D structureCID 15005335C31H28ClN5O3554.0476 / 25.2No
784032D structure2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(2-chlorophenyl)-5-carbamoyl-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl esterC29H26ClN5O3528.0096 / 24.3No
794342D structureCHEMBL133921C26H26N4O410.5214 / 03.4Yes
822602D structureCHEMBL103753C26H26N4O2426.525 / 12.2Yes
842602D structureCHEMBL164665C37H36ClN7O3S694.25110 / 13.8No
5536922D structureGinkgolide AC20H24O9408.4039 / 20.6Yes
849662D structureCHEMBL338940C26H26N4O2426.525 / 12.2Yes
864532D structureCHEMBL347593C30H47IN2O2594.6223 / 0N/ANo
869082D structureCHEMBL320676C24H27N5O401.5145 / 11.5Yes
890382D structureCHEMBL119847C23H19N5O381.4394 / 03.1Yes
906882D structureCHEMBL132655C27H26ClN3O443.9753 / 05.0Yes
932372D structureCHEMBL349150C40H41ClN6O2S705.3188 / 07.9No
978172D structureCHEMBL131690C25H27N3O385.5113 / 03.3Yes
1009192D structureCHEMBL431049C29H31N5O3497.5996 / 13.0Yes
1036262D structureCHEMBL554463C21H26ClN5O399.9235 / 2N/AN/A
1038252D structureCHEMBL101342C27H28N6O3484.567 / 22.2Yes
1044192D structureCHEMBL323798C39H38ClN7O4S736.28810 / 06.4No
1064742D structureCHEMBL103231C27H29N5O3S503.6217 / 12.5No
1065922D structureCHEMBL545773C27H30ClN5O476.0215 / 2N/AN/A
5537862D structure7alpha-Cl-ginkgolide BC20H23ClO10458.84410 / 3-0.1Yes
1104522D structureCHEMBL336816C27H29N5O439.5635 / 13.1Yes
1104692D structureCHEMBL100547C27H29N5O439.5635 / 14.0Yes
1107992D structureCHEMBL157123C31H47IN2O4638.6315 / 0N/ANo
1121422D structureCHEMBL349582C31H47IN2O4638.6315 / 0N/ANo
1123712D structureCHEMBL103801C27H29N5O439.5635 / 12.6Yes
1127402D structureCHEMBL100853C21H25N5O363.4655 / 10.9Yes
1137232D structureCHEMBL335974C34H32O12632.61812 / 23.2No
1193222D structureCHEMBL552771C19H29ClN4O364.9184 / 1N/AN/A
1212522D structureCHEMBL552805C28H32ClN5O490.0485 / 2N/AN/A
1214012D structureCHEMBL164123C39H40ClN7O3S722.30510 / 06.8No
1223012D structureCHEMBL421204C22H26N6O2406.495 / 20.6Yes
1224622D structureCHEMBL541330C20H24ClN3O5421.8786 / 1N/AN/A
1234572D structureCHEMBL116198C22H15Cl2N5O436.2964 / 14.2Yes
1272392D structureCHEMBL3215980C20H24Cl2N4O407.3394 / 2N/AN/A
1311502D structureCID 15005355C32H29ClN4O3S585.1197 / 26.5No
5539482D structure7alpha-NHMe-ginkgolide BC21H27NO10453.44411 / 4-1.1No
1324502D structureCHEMBL100522C26H27N5O2441.5356 / 11.5Yes
1388032D structureCHEMBL340989C27H27N5O2453.5465 / 12.6Yes
1422372D structureCHEMBL337840C34H34O12634.63412 / 32.0No
5540012D structure7alpha-OCOCH2Ph-ginkgolide BC28H30O12558.53612 / 30.8No
1450862D structureCHEMBL351224C45H45ClN8O3S813.41811 / 07.7No
1464472D structure2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(2-pyridinyl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl esterC33H29N7O3571.6418 / 23.9No
1500752D structureCHEMBL100497C28H31N5O453.595 / 12.9Yes
1504952D structureApafantC22H22ClN5O2S455.9616 / 01.1Yes
1519782D structure2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(1,3-benzodioxol-4-yl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl esterC35H30N6O5614.6629 / 24.7No
1521342D structureCHEMBL335310C29H29F3N2O11638.54916 / 31.7No
1542922D structureCHEMBL339997C27H25F4N3O10627.50216 / 23.0No
1558712D structureCHEMBL335044C26H26N4O410.5214 / 03.5Yes
1563502D structureCHEMBL346722C44H73IN2O4820.9825 / 0N/ANo
1587932D structureCHEMBL134143C27H25N3O407.5173 / 03.8Yes
1593172D structureCHEMBL100281C27H28N6O3484.566 / 21.8Yes
1628812D structure2-[4-(2-Methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-4-(4-cyanophenyl)-5-(2-pyridinylcarbamoyl)-6-methyl-1,4-dihydropyridine-3-carboxylic acid ethyl esterC35H29N7O3595.6638 / 24.7No
1649592D structureCHEMBL103465C27H31N3O2429.5644 / 13.1Yes
1659152D structureCHEMBL100340C24H29N5O3435.5286 / 01.7Yes
1664222D structureCHEMBL154856C30H45F3N2O5S602.7548 / 1N/ANo
1700202D structureCHEMBL155003C31H47IN2O4638.6315 / 1N/ANo
1735372D structureCHEMBL99833C22H26N4O2378.4765 / 11.3Yes
1735952D structureCHEMBL130606C34H34O11618.63511 / 23.0No
1753602D structureCHEMBL133457C27H29N5O439.5635 / 12.6Yes
1758842D structureCHEMBL103761C35H37N5O543.7155 / 04.8No
1768812D structureCID 15005334C33H32ClN5O3582.1016 / 26.0No
1772182D structureCHEMBL103619C25H27N5O3445.5236 / 00.7Yes
1799312D structureCHEMBL423891C20H20N4O332.4074 / 02.0Yes
1857232D structureCHEMBL154205C30H45IN2O3608.6054 / 0N/ANo

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