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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameProstaglandin E2 receptor EP2 subtype
SpeciesMus musculus (Mouse)
GenePtger2
SynonymEP2 receptor
PGE receptor EP2 subtype
PGE2 receptor EP2 subtype
prostaglandin E receptor 2 (subtype EP2), 53kDa
prostanoid EP2 receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length362
Amino acid sequenceMDNFLNDSKLMEDCKSRQWLLSGESPAISSVMFSAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESHACTYFAFTMTFFSLATMLMLFAMALERYLSIGYPYFYRRHLSRRGGLAVLPVIYGASLLFCSLPLLNYGEYVQYCPGTWCFIRHGRTAYLQLYATMLLLLIVAVLACNISVILNLIRMHRRSRRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAICSLPFTIFAYMDETSSLKEKWDLRALRFLSVNSIIDPWVFAILRPPVLRLMRSVLCCRTSLRTQEAQQTSCSTQSSASKQTDLCGQL
UniProtQ62053
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2488
IUPHAR341
DrugBankN/A

Known ligands

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Total entries: 270
Page:  / 3 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
30252D structureCHEMBL1929538C21H29NO6S423.5247 / 21.7Yes
78162D structureCHEMBL1929550C23H33NO4S419.585 / 22.8Yes
83312D structureCHEMBL1094419C30H35NO4473.6134 / 26.4No
83352D structureCHEMBL596956C30H35NO4473.6134 / 26.4No
99822D structureCHEMBL1094160C30H33F2NO4509.5946 / 26.6No
116402D structureAH 6809C17H14O5298.2945 / 13.9Yes
5533162D structureCicaprostC22H30O5374.4775 / 32.1Yes
127732D structureCID 53394056C22H30O5374.4775 / 32.1Yes
131462D structureCHEMBL1929526C23H33NO5403.5195 / 22.2Yes
159452D structureCHEMBL2315052C24H23Cl2FN2O2461.3584 / 06.2No
177952D structureCHEMBL2315053C27H25Cl2FN2O2499.4074 / 17.0No
186002D structureCHEMBL305126C21H28O6S2440.5698 / 32.3Yes
192652D structureacrylic acid derivative, 4C25H22N2O3398.4624 / 15.0Yes
194982D structureCHEMBL2037291C29H29N3O5S2563.6879 / 25.1No
206232D structureCHEMBL186735C26H23NO5429.4725 / 15.0Yes
236272D structureCHEMBL595830C25H24N2O4416.4775 / 14.3Yes
4659952D structureCHEMBL3586309C24H22N2O2S402.5125 / 04.5Yes
254832D structureCHEMBL1819607C27H28N2O5460.536 / 14.4Yes
300492D structureCHEMBL2315056C26H17Cl4FN2O4S614.296 / 17.6No
317082D structureCHEMBL1095117C29H31F2NO4495.5676 / 26.6No
5534222D structureONO-AE1-329C23H32O6S2468.6238 / 32.3Yes
350532D structureCHEMBL1819611C27H28N2O5460.536 / 24.5Yes
354772D structureCHEMBL303532C24H34O6S2482.658 / 32.8Yes
367912D structureCHEMBL591034C25H25NO4403.4784 / 24.4Yes
383632D structureCHEMBL1091741C31H27F2N3O4S575.6317 / 15.8No
401972D structureCHEMBL1929527C22H31NO5S421.5526 / 21.6Yes
413522D structureindomethacinC19H16ClNO4357.794 / 14.3Yes
416322D structureCHEMBL62885C24H38O5406.5635 / 34.1Yes
421182D structureCHEMBL364421C23H25NO5395.4555 / 14.9Yes
446272D structureCHEMBL1813120C29H28N2O5484.5526 / 15.4No
460842D structureCHEMBL1929545C21H29NO3S375.5274 / 23.1Yes
465242D structureCHEMBL2036325C27H24ClN3O4S3586.1369 / 25.6No
490342D structureCHEMBL1929539C19H25NO4S2395.5326 / 22.6Yes
511622D structureCHEMBL1091743C30H26F2N4O4S576.6198 / 25.1No
512002D structureCHEMBL595159C25H20N2O3396.4464 / 15.1No
524492D structureCHEMBL60555C19H32O5S372.526 / 32.2Yes
535382D structureCHEMBL1095769C32H39NO4501.6674 / 27.1No
542652D structureCHEMBL1094813C32H39NO4501.6674 / 27.1No
558262D structureCHEMBL1929528C23H32O5S420.5646 / 22.5Yes
611122D structureacrylic acid derivative, 9C22H22N2O4378.4285 / 13.6Yes
5535812D structureDoprostonC20H34O4338.4884 / 24.2Yes
657872D structure11-deoxy Prostaglandin E1C20H34O4338.4884 / 24.2Yes
706652D structureCHEMBL2036319C27H28N2O5S2524.658 / 24.5No
733572D structureCHEMBL1813115C28H26N2O5470.5256 / 15.0Yes
5536412D structureRivenprostC24H34O6S450.597 / 21.8Yes
762122D structureCHEMBL1819606C26H26N2O5446.5036 / 14.0Yes
768992D structureCHEMBL361098C22H23NO5381.4285 / 14.7Yes
775162D structureacrylic acid derivative, 6C24H28O5396.4835 / 25.2No
781392D structureCHEMBL1813117C28H25ClN2O5504.9676 / 15.9No
793072D structureCHEMBL292717C24H34O6S2482.658 / 32.9Yes
793362D structureCHEMBL1957434C22H24ClNO4S433.9475 / 24.0Yes
885252D structureCHEMBL62888C21H28O6S2440.5698 / 32.3Yes
910182D structureCHEMBL1957436C26H25ClN2O4S2529.0667 / 25.1No
943382D structureCHEMBL62868C19H32O5S372.526 / 32.2Yes
960752D structureCHEMBL1933718C24H27NO4393.4834 / 23.3Yes
969382D structureCHEMBL1094814C29H34N2O4474.6015 / 25.3No
975542D structureCHEMBL2037292C27H24ClN3O5S2570.0759 / 25.0No
989182D structureCHEMBL183933C23H25NO4379.4564 / 15.3No
1002492D structure15(R)-Prostaglandin E1C20H34O5354.4875 / 33.2Yes
1002512D structurealprostadilC20H34O5354.4875 / 33.2Yes
1073662D structureCHEMBL365829C28H25NO5455.515 / 15.5No
1149902D structureacrylic acid derivative, 16C28H24O4424.4964 / 16.5No
1156272D structureILOPROSTC22H32O4360.4944 / 32.8Yes
5538482D structureILOPROSTC22H32O4360.4944 / 32.8Yes
1166332D structureUNII-CQ5912425UC20H14Cl2FNO3406.2345 / 15.5No
1168512D structureCHEMBL293242C23H36O5392.5365 / 33.6Yes
1168552D structureCHEMBL294585C23H36O5392.5365 / 33.6Yes
1206562D structureCHEMBL293856C22H30O6S2454.5968 / 32.0Yes
1227782D structureCHEMBL602337C28H31NO4445.5594 / 25.6No
1228192D structureCHEMBL182555C22H23NO4365.4294 / 14.6Yes
1246142D structureCHEMBL2036314C28H31NO5S493.6186 / 24.0Yes
1275432D structureCHEMBL64188C19H32O5S372.526 / 32.7Yes
1277612D structureCHEMBL62779C23H32O6S2468.6238 / 32.4Yes
1328002D structureCHEMBL439934C24H33FO5420.5216 / 33.0Yes
1342672D structureCHEMBL1813118C28H25FN2O5488.5157 / 15.4No
1361082D structureCHEMBL1929542C20H24F3NO4S2463.539 / 23.5Yes
1395552D structureCHEMBL64483C22H34O5378.5095 / 33.0Yes
1400142D structureCHEMBL1929531C21H29NO5S407.5256 / 22.9Yes
1433702D structureCHEMBL64217C18H30O5S2390.5537 / 32.7Yes
1434282D structureacrylic acid derivative, 12C25H22N2O3398.4624 / 14.7Yes
1438562D structureCHEMBL64187C19H32O5S372.526 / 32.2Yes
1439242D structureacrylic acid derivative, 17C28H24O4424.4964 / 16.5No
1453032D structureCHEMBL64072C23H33FO5S440.577 / 32.8Yes
1458692D structureSCHEMBL2962411C23H21Cl2FN2O4S511.3896 / 15.7No
1460942D structure99946-24-4C21H34O4350.4994 / 33.4Yes
5540072D structureIsocarbacyclinC21H34O4350.4994 / 33.4Yes
1474692D structureCHEMBL2036326C28H27N3O5S2549.669 / 24.7No
4811412D structure4-(7-(5-Fluoro-1H-indole-1-yl)-9-chloro-2,3,4,5-tetrahydro-1,4-benzooxazepine-4-yl)methylpyridine-2(1H)-oneC23H19ClFN3O2423.8724 / 13.3Yes
1481262D structureCHEMBL222715C21H29NO4359.4664 / 23.3Yes
1483432D structureCHEMBL185277C26H31NO5437.5365 / 16.1No
1525882D structureCHEMBL1933723C21H24N2O4S2432.5537 / 23.2Yes
1541452D structureCHEMBL361457C26H23NO4413.4734 / 15.3No
1542232D structureCHEMBL1933726C23H25F3N2O5S2530.57711 / 23.6No
1544582D structureCHEMBL1813116C29H28N2O5484.5526 / 15.4No
1587242D structureCHEMBL2036315C26H32N2O5S484.6117 / 22.3Yes
1587522D structureCHEMBL2315050C24H23Cl2FN2O2461.3584 / 16.6No
1589082D structureCHEMBL1929533C20H24F3NO5S447.4699 / 22.9Yes
1601152D structureCHEMBL2037289C28H27N3O5S2549.669 / 24.7No
1606722D structureCHEMBL603633C24H22N2O4402.455 / 14.6Yes
1635702D structureCHEMBL2036312C27H30N2O5S494.6067 / 23.4Yes

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