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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameProstaglandin E2 receptor EP2 subtype
SpeciesRattus norvegicus (Rat)
GenePtger2
SynonymEP2 receptor
PGE receptor EP2 subtype
PGE2 receptor EP2 subtype
prostaglandin E receptor 2 (subtype EP2), 53kDa
Prostanoid EP2 receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length357
Amino acid sequenceMDNSFNDSRRVENCESRQYLLSDESPAISSVMFTAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESRACTYFAFTMTFFSLATMLMLFAMALERYLAIGHPYFYRRRVSRRGGLAVLPAIYGVSLLFCSLPLLNYGEYVQYCPGTWCFIQHGRTAYLQLYATVLLLLIVAVLGCNISVILNLIRMQLRSKRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAVCSLPFTIFAYMDETSSRKEKWDLRALRFLSVNSIIDPWVFVILRPPVLRLMRSVLCCRTSLRAPEAPGASCSTQQTDLCGQL
UniProtQ62928
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4909
IUPHAR341
DrugBankN/A

Known ligands

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Total entries: 91
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
114282D structureCHEMBL383515C24H28ClNO4429.9414 / 24.4Yes
5533052D structureAH 6809C17H14O5298.2945 / 13.9Yes
182402D structureCHEMBL551951C17H35NO5S365.5296 / 23.1Yes
194962D structureCHEMBL2037291C29H29N3O5S2563.6879 / 25.1No
200282D structureCHEMBL382197C28H31NO4S477.6195 / 25.4No
230352D structureCHEMBL46395C22H30F3NO4429.487 / 23.9Yes
5533822D structureprostaglandin D2C20H32O5352.4715 / 32.6Yes
4659932D structureCHEMBL3586309C24H22N2O2S402.5125 / 04.5Yes
347712D structureCHEMBL553468C19H31NO4S369.525 / 13.8Yes
427832D structureCHEMBL208080C24H28FNO4413.4895 / 23.8Yes
465202D structureCHEMBL2036325C27H24ClN3O4S3586.1369 / 25.6No
489332D structureCHEMBL206774C27H35NO5453.5795 / 24.5Yes
558432D structureCHEMBL558671C21H27NO4S389.515 / 13.7Yes
5535842D structureDoprostonC20H34O4338.4884 / 24.2Yes
663992D structureCHEMBL427035C24H29NO4395.4994 / 23.7Yes
706622D structureCHEMBL2036319C27H28N2O5S2524.658 / 24.5No
745492D structureCHEMBL208411C30H33NO4471.5974 / 25.4No
759772D structureCHEMBL559955C21H27NO4S389.515 / 14.2Yes
5536782D structure17-phenyl-trinor-PGE2C23H30O5386.4885 / 32.8Yes
910172D structureCHEMBL1957436C26H25ClN2O4S2529.0667 / 25.1No
975502D structureCHEMBL2037292C27H24ClN3O5S2570.0759 / 25.0No
5537492D structurealprostadilC20H34O5354.4875 / 33.2Yes
1096052D structureCHEMBL425409C22H30N2O4386.4925 / 22.7Yes
1142862D structureCHEMBL425950C24H31NO4S429.5755 / 24.6Yes
5538512D structureILOPROSTC22H32O4360.4944 / 32.8Yes
1209422D structureCHEMBL559820C22H29NO4S403.5375 / 14.6Yes
1282152D structureCHEMBL554823C20H33NO5S399.5466 / 23.1Yes
1343512D structureCHEMBL203076C21H31NO5377.4815 / 32.7Yes
1433512D structureCHEMBL207237C22H26FNO4S419.5116 / 23.9Yes
1474712D structureCHEMBL2036326C28H27N3O5S2549.669 / 24.7No
4811462D structure4-(7-(5-Fluoro-1H-indole-1-yl)-9-chloro-2,3,4,5-tetrahydro-1,4-benzooxazepine-4-yl)methylpyridine-2(1H)-oneC23H19ClFN3O2423.8724 / 13.3Yes
1481292D structureCHEMBL222715C21H29NO4359.4664 / 23.3Yes
1601182D structureCHEMBL2037289C28H27N3O5S2549.669 / 24.7No
1635212D structureUNII-XO355X0D3BC23H26F3NO4S469.5198 / 24.7Yes
1720152D structureCHEMBL549869C21H27NO5S405.5096 / 13.5Yes
1833232D structureCHEMBL2037290C28H27N3O5S2549.669 / 24.7No
1849382D structureCHEMBL223151C18H31NO4S357.5095 / 22.3Yes
1854132D structureCHEMBL559561C18H29NO5S371.4926 / 13.0Yes
1877932D structureCHEMBL2036324C27H25N3O4S3551.6949 / 25.0No
1909612D structureCHEMBL549461C19H31NO4S369.525 / 14.0Yes
1914152D structureCHEMBL559760C22H29NO4S403.5375 / 14.6Yes
5542662D structureU 46619C21H34O4350.4994 / 23.9Yes
2033802D structureCHEMBL425243C22H26ClNO4S435.9635 / 24.4Yes
5543152D structureTaprenepagC24H22N4O5S478.5238 / 12.5Yes
2214882D structureCHEMBL379746C22H26ClNO4S435.9635 / 24.4Yes
2228792D structureCHEMBL204058C21H30ClNO4395.9244 / 23.6Yes
2271802D structureCHEMBL562291C21H33NO5S411.5576 / 13.7Yes
5544462D structureDpt-prostaglandin E1C22H30O5374.4775 / 23.5Yes
2361852D structureCHEMBL2036320C28H30N2O4S2522.6787 / 25.2No
5545422D structurebutaprost acidC23H38O5394.5525 / 33.9Yes
2575962D structureCHEMBL562411C21H35NO5S413.5736 / 23.6Yes
2611032D structureCHEMBL2036318C27H28N2O4S2508.6517 / 24.9No
2616292D structureCHEMBL379785C28H31NO4S477.6195 / 25.4No
2622062D structureCHEMBL1957437C30H28N2O4S2544.6847 / 25.7No
2638162D structureCHEMBL2036323C27H25N3O5S2535.6339 / 24.4No
2703482D structureCHEMBL2036322C28H26N2O5S2534.6458 / 24.9No
5546282D structuredinoprostC20H34O5354.4875 / 42.7Yes
2744412D structureCHEMBL2036321C28H30N2O4S2522.6787 / 25.2No
2801442D structureMK-2894C25H22F3NO3S473.517 / 25.9No
2848882D structureCHEMBL556333C22H29NO4S403.5375 / 13.9Yes
2853452D structureCHEMBL205819C23H35NO5405.5355 / 22.7Yes
3002312D structureCHEMBL378968C22H26FNO4S419.5116 / 23.9Yes
3101332D structureCHEMBL541516C26H30N2O4S466.5966 / 14.8Yes
3110522D structureCHEMBL562825C22H29NO5S419.5366 / 14.4Yes
3114382D structureCHEMBL381755C30H33NO5487.5965 / 25.3No
3142272D structureCHEMBL383339C24H37NO5419.5625 / 23.1Yes
3200832D structureCHEMBL1933722C21H24N2O4S2432.5537 / 23.2Yes
3215972D structureCHEMBL380839C25H28F3NO4463.4977 / 24.6Yes
3248122D structureCHEMBL208510C22H30F3NO5445.4798 / 24.2Yes
3291782D structureCHEMBL556416C25H31N3O5S485.5997 / 13.4Yes
3316132D structureCHEMBL1957435C26H26N2O4S2494.6247 / 24.5Yes
3351152D structureCHEMBL549530C27H30ClNO4S500.055 / 16.1No
3506362D structureCHEMBL549663C21H27NO5S405.5096 / 13.9Yes
3589672D structureCHEMBL550619C22H29NO4S403.5375 / 14.3Yes
3610692D structureCHEMBL208399C27H35NO4437.584 / 24.6Yes
3626892D structureCHEMBL559623C15H31NO5S337.4756 / 22.2Yes
3768322D structureCHEMBL203780C21H31NO4361.4824 / 23.0Yes
3769732D structureCHEMBL549870C22H29NO4S403.5375 / 14.1Yes
3783152D structureEvatanepagC25H28N2O5S468.5687 / 14.2Yes
3793742D structureCHEMBL559560C16H33NO5S351.5026 / 22.5Yes
5552032D structure19(R)-hydroxy-PGE2C20H32O6368.476 / 41.3Yes
3831652D structureCHEMBL541517C24H28N2O4S2472.6187 / 14.9Yes
3901012D structureProstaglandin E2C20H32O5352.4715 / 32.8Yes
3960812D structureCHEMBL208410C26H29NO4S451.5815 / 25.0Yes
3972622D structureCHEMBL42027C19H33NO4339.4764 / 22.9Yes
4099202D structureCHEMBL382029C22H27NO4S401.5215 / 23.8Yes
4195012D structureCHEMBL559065C27H31NO4S465.6085 / 15.5No
4279472D structureCHEMBL2113220C22H33NO4375.5094 / 23.4Yes
4279492D structureCHEMBL208407C22H33NO4375.5094 / 23.4Yes
4365022D structureCHEMBL444798C24H28FNO4413.4895 / 23.8Yes
4385472D structureCHEMBL550015C16H33NO5S351.5026 / 22.4Yes

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