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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameNeurotensin receptor type 2
SpeciesRattus norvegicus (Rat)
GeneNtsr2
SynonymNT-R-2
neurotensin receptor type 2
NTR2
High-affinity levocabastine-sensitive neurotensin receptor
NTS2 receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length416
Amino acid sequenceMETSSPWPPRPSPSAGLSLEARLGVDTRLWAKVLFTALYSLIFAFGTAGNALSVHVVLKARAGRPGRLRYHVLSLALSALLLLLVSMPMELYNFVWSHYPWVFGDLGCRGYYFVRELCAYATVLSVASLSAERCLAVCQPLRARRLLTPRRTRRLLSLVWVASLGLALPMAVIMGQKHEVESADGEPEPASRVCTVLVSRATLQVFIQVNVLVSFALPLALTAFLNGITVNHLMALYSQVPSASAQVSSIPSRLELLSEEGLLGFITWRKTLSLGVQASLVRHKDASQIRSLQHSAQVLRAIVAVYVICWLPYHARRLMYCYIPDDGWTNELYDFYHYFYMVTNTLFYVSSAVTPILYNAVSSSFRKLFLESLGSLCGEQHSLVPLPQEAPESTTSTYSFRLWGSPRNPSLGEIQV
UniProtQ63384
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5106
IUPHAR310
DrugBankN/A

Known ligands

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Total entries: 39
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
284422D structureCHEMBL3290100C29H29N3O4483.5685 / 26.4No
322592D structureCHEMBL3290101C29H29N3O5499.5676 / 25.6No
363392D structureCHEMBL3290096C28H27ClN4O5534.9977 / 25.2No
5229232D structureCHEMBL3817879C29H34FN3O5523.6057 / 26.2No
489632D structureCHEMBL3290099C30H31N3O5513.5946 / 26.4No
613472D structureCHEMBL3290105C25H26FN3O5467.4977 / 24.4Yes
662052D structureCHEMBL342252C38H64N12O8817.00611 / 11-4.0No
681322D structureCHEMBL1172376C41H70ClN9O8852.51610 / 8N/ANo
4445192D structureCHEMBL3356853C24H24ClN3O5469.9227 / 24.6Yes
720682D structureMeclinertantC32H31ClN4O5587.0737 / 25.8No
827302D structureCHEMBL3290106C24H24FN3O4437.4716 / 24.4Yes
1136602D structureCHEMBL3290091C29H29ClN4O5549.0247 / 26.0No
1298312D structureCHEMBL3290097C27H25ClN4O5520.977 / 24.7No
1458572D structureCHEMBL3290095C29H29ClN4O5549.0247 / 25.7No
4480582D structure5-[(6-chloro-4-phenylquinazolin-2-yl)amino]-2-hydroxybenzoic acidC21H14ClN3O3391.8116 / 35.4No
1983352D structureCHEMBL3290089C31H31ClN4O3543.0645 / 16.4No
1983952D structureSR142948AC39H51N5O6685.8668 / 23.6No
2002372D structureCHEMBL3290103C29H30FN3O5519.5737 / 25.0No
4497962D structureCHEMBL3356855C25H26ClN3O5483.9497 / 25.4No
2339022D structureCHEMBL1172376C41H70N9O8+817.0669 / 82.8No
4515132D structureCHEMBL3403508C24H24FN3O4437.4716 / 25.4No
2563442D structureNEUROTENSINC78H121N21O201672.9523 / 21-3.7No
2714742D structureSR-48527C29H29ClN4O5549.0247 / 26.0No
4526442D structureCHEMBL3356856C24H26FN3O5455.4867 / 24.5Yes
4529372D structureCHEMBL3356854C23H24ClN3O5457.9117 / 24.7Yes
2986152D structureCHEMBL3290092C28H27ClN4O4518.9986 / 26.0No
3007112D structureCHEMBL3290098C27H25ClN4O4504.9716 / 25.2No
4543922D structureCHEMBL3326831C25H26F3N3O6S553.55310 / 34.5No
4549122D structureCHEMBL3403507C25H26FN3O5467.4977 / 25.3No
4549532D structureCHEMBL3403504C29H31ClN4O4535.0417 / 23.5No
3387472D structureCHEMBL3290102C28H27N3O4469.5415 / 25.6No
5315322D structureCHEMBL3818506C27H30FN3O5495.5517 / 25.1No
3850472D structureCHEMBL3290104C26H28FN3O5481.5247 / 25.2No
4569842D structureCHEMBL3403505C28H27ClN4O5534.9977 / 26.1No
3864542D structureCHEMBL3290094C31H33ClN4O5577.0787 / 26.8No
3936412D structureCHEMBL3290093C27H23ClF2N4O3524.9537 / 26.3No
4577352D structureCHEMBL3326832C23H27N3O5S457.5456 / 33.7Yes
4056562D structureCHEMBL3290090C29H29ClN4O5549.0247 / 26.0No
4592292D structureCHEMBL3403506C29H29N3O5499.5676 / 26.5No

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