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| Name | Substance-K receptor |
|---|---|
| Species | Cavia porcellus (Guinea pig) |
| Gene | TACR2 |
| Synonym | Neurokinin A receptor NK-2 receptor NK-2R SKR Tachykinin receptor 2 |
| Disease | N/A for non-human GPCRs |
| Length | 402 |
| Amino acid sequence | MGACVIVTNTNISSGLESNTTGITAFSMPTWQLALWATAYLALVLVAVTGNATVTWIILAHQRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAIDRYMAIVHPFQPRLSAPSTKAVIGGIWLVALALAFPQCFYSTITEDEGATKCVVAWPEDSRDKSLLLYHLVVIVLIYLLPLTVMFVAYSIIGLTLWRRAVPRHQAHGANLRHLQAKKKFVKTMVLVVVTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNRRFRSGFRLAFRCCPWVTPTEEDKLELTHTPSFSLRVNRCHTKEILFMAGDTVPSEATNGQAGGPQDRESVELSSLPGCRAGPSILAKASS |
| UniProt | Q64077 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2647 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 761 |  CHEMBL57589 | C27H34Cl2N2O3 | 505.48 | 4 / 0 | 5.8 | No |
| 2253 |  CHEMBL236661 | C31H40N4O3S | 548.746 | 5 / 4 | 5.3 | No |
| 2494 |  Substance P | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
| 3695 |  CHEMBL242626 | C36H40N6O4S | 652.814 | 7 / 3 | 4.6 | No |
| 9570 |  CHEMBL355506 | C28H29Cl2N5O3 | 554.472 | 6 / 1 | 3.2 | No |
| 10952 |  CHEMBL395972 | C37H45F3N4O4S | 698.846 | 9 / 3 | 6.6 | No |
| 13363 |  CHEMBL394607 | C36H45N5O5S | 659.846 | 7 / 3 | 3.9 | No |
| 13754 |  CHEMBL352734 | C29H30Cl2N4O3 | 553.484 | 5 / 1 | 4.2 | No |
| 15242 |  CHEMBL394420 | C35H38N4O3S | 594.774 | 5 / 3 | 6.0 | No |
| 17567 |  ELEDOISIN | C54H85N13O15S | 1188.41 | 17 / 14 | -3.6 | No |
| 18248 |  CHEMBL67508 | C32H39Cl4N5O4 | 699.495 | 6 / 1 | 5.6 | No |
| 18249 |  CHEMBL66635 | C32H39Cl4N5O4 | 699.495 | 6 / 1 | 5.6 | No |
| 18251 |  CHEMBL441252 | C32H39Cl4N5O4 | 699.495 | 6 / 1 | 5.6 | No |
| 19021 |  GR-159897 | C23H27FN2O2S | 414.539 | 5 / 1 | 3.4 | Yes |
| 23622 |  UNII-G9BL4978MZ | C27H25Cl2F6N3O3 | 624.405 | 9 / 2 | 6.2 | No |
| 24364 |  CHEMBL354170 | C32H34Cl2N4O4 | 609.548 | 5 / 2 | 4.1 | No |
| 29349 |  CHEMBL443237 | C30H31Cl2N3O3 | 552.496 | 4 / 1 | 5.0 | No |
| 35934 |  CHEMBL359587 | C31H34BrCl2N3O3 | 647.435 | 4 / 2 | 5.9 | No |
| 40537 |  MEN-10627 | C38H48N8O7S | 760.911 | 8 / 8 | 2.0 | No |
| 42666 |  CHEMBL171876 | C31H35Cl2N3O6S | 648.596 | 8 / 1 | 4.6 | No |
| 44882 |  CHEMBL363727 | C31H35Cl2N3O3 | 568.539 | 4 / 2 | 5.7 | No |
| 49104 |  CHEMBL353480 | C33H37Cl2N3O6 | 642.574 | 8 / 0 | 5.3 | No |
| 50623 |  CHEMBL507334 | C36H47ClN4O4 | 635.246 | 5 / 3 | 5.4 | No |
| 51791 |  CHEMBL231261 | C29H37Cl2N5O3S | 606.607 | 5 / 4 | 4.5 | No |
| 52732 |  CHEMBL66106 | C30H36Cl4N4O3 | 642.443 | 5 / 0 | 6.7 | No |
| 52735 |  CHEMBL68060 | C30H36Cl4N4O3 | 642.443 | 5 / 0 | 6.7 | No |
| 53166 |  CHEMBL354288 | C34H39Cl2N3O6 | 656.601 | 7 / 1 | 5.2 | No |
| 54420 |  CHEMBL171725 | C34H38Cl2N2O6 | 641.586 | 7 / 0 | 5.7 | No |
| 55085 |  CHEMBL301437 | C26H34Cl2N2O2 | 477.47 | 3 / 1 | 5.5 | No |
| 57460 |  CHEMBL237048 | C36H41N5O3S | 623.816 | 6 / 3 | 5.3 | No |
| 57731 |  CHEMBL171719 | C33H36Cl2N2O7S | 675.618 | 8 / 0 | 4.8 | No |
| 64958 |  CHEMBL172572 | C29H30Cl2N4O3 | 553.484 | 5 / 1 | 3.9 | No |
| 67394 |  CHEMBL242625 | C32H39N5O4S | 589.755 | 6 / 3 | 3.5 | No |
| 69872 |  CHEMBL244364 | C31H37ClN4O4S | 597.171 | 6 / 3 | 4.9 | No |
| 69986 |  CHEMBL171704 | C34H37Cl2N3O6 | 654.585 | 7 / 0 | 5.1 | No |
| 70431 |  CHEMBL1083875 | C36H44N4O3S | 612.833 | 6 / 2 | 6.5 | No |
| 72111 |  CHEMBL1083858 | C35H46N4O3S | 602.838 | 6 / 2 | 6.0 | No |
| 72872 |  CHEMBL299377 | C35H41Cl2N3O2 | 606.632 | 3 / 0 | 7.0 | No |
| 73557 |  CHEMBL243725 | C29H38IN5O4 | 647.558 | 5 / 4 | 3.3 | No |
| 74758 |  CHEMBL354183 | C33H36Cl2N2O6 | 627.559 | 7 / 0 | 5.3 | No |
| 75463 |  CHEMBL417940 | C26H32Cl2N2O2 | 475.454 | 3 / 0 | 5.4 | No |
| 78270 |  CHEMBL237097 | C36H50N4O3S | 618.881 | 5 / 3 | 7.7 | No |
| 80592 |  CHEMBL397264 | C33H40N4O4 | 556.707 | 5 / 3 | 4.2 | No |
| 81246 |  CHEMBL170936 | C35H41Cl2N3O6 | 670.628 | 7 / 0 | 5.5 | No |
| 83278 |  CHEMBL172938 | C24H28N4O3 | 420.513 | 3 / 4 | 3.2 | Yes |
| 83737 |  CHEMBL1084765 | C36H48N4O4 | 600.804 | 6 / 2 | 5.5 | No |
| 85438 |  CHEMBL1083855 | C37H50N4O3S | 630.892 | 6 / 2 | 6.7 | No |
| 85668 |  CHEMBL1083861 | C37H48N4O3S | 628.876 | 6 / 2 | 6.1 | No |
| 88278 |  CHEMBL244566 | C31H37ClN4O4S | 597.171 | 6 / 3 | 4.9 | No |
| 91073 |  CHEMBL354756 | C32H36Cl2N4O6 | 643.562 | 8 / 1 | 3.8 | No |
| 91653 |  CHEMBL355387 | C33H37FN2O6S | 608.725 | 9 / 0 | 3.6 | No |
| 92441 |  CHEMBL58331 | C27H35Cl2N3O2 | 504.496 | 3 / 1 | 5.2 | No |
| 94203 |  CHEMBL424578 | C32H35Cl2N3O5 | 612.548 | 6 / 1 | 4.9 | No |
| 94361 |  CHEMBL1083880 | C37H45N5O3S | 639.859 | 5 / 2 | 6.1 | No |
| 95221 |  CHEMBL1083873 | C36H44N4O2S2 | 628.894 | 6 / 2 | 7.1 | No |
| 95701 |  CHEMBL171381 | C31H35Cl2N3O6 | 616.536 | 8 / 1 | 4.1 | No |
| 98471 |  CHEMBL1083864 | C37H49N3O4S | 631.876 | 6 / 2 | 6.6 | No |
| 98765 |  CHEMBL169318 | C29H33Cl2N5O5 | 602.513 | 9 / 0 | 4.2 | No |
| 100009 |  CHEMBL1083869 | C38H45FN4O2S | 640.862 | 6 / 2 | 7.5 | No |
| 104749 |  CHEMBL184391 | C29H31Cl2N3O4 | 556.484 | 5 / 1 | 5.8 | No |
| 106388 |  CHEMBL352615 | C34H39Cl2N3O7S | 704.66 | 9 / 0 | 5.2 | No |
| 107676 |  CHEMBL394419 | C35H38N4O4S | 610.773 | 6 / 3 | 5.2 | No |
| 107745 |  CHEMBL244362 | C36H45BrN4O4S | 709.744 | 6 / 3 | 6.4 | No |
| 110443 |  CHEMBL398028 | C35H38N4O4S | 610.773 | 6 / 3 | 5.1 | No |
| 112231 |  CHEMBL1083879 | C37H48N4O4S | 644.875 | 6 / 2 | 5.7 | No |
| 112521 |  NEUROKININ A | C50H80N14O14S | 1133.33 | 18 / 16 | -4.8 | No |
| 112533 |  Substance K | C50H80N14O14S | 1133.33 | 18 / 16 | -4.8 | No |
| 112606 |  CHEMBL425179 | C30H31Cl2N3O2S | 568.557 | 5 / 1 | 7.3 | No |
| 113736 |  CHEMBL353596 | C33H37ClN2O6S | 625.177 | 8 / 0 | 4.2 | No |
| 114795 |  CHEMBL1083863 | C38H51N3O3S | 629.904 | 5 / 2 | 8.0 | No |
| 123141 |  CHEMBL395971 | C36H45FN4O4S | 648.838 | 7 / 3 | 5.8 | No |
| 126875 |  CHEMBL1083868 | C35H42N6O2S | 610.821 | 7 / 2 | 6.3 | No |
| 129126 |  GR100679 | C34H44N6O5 | 616.763 | 5 / 5 | 3.4 | No |
| 131846 |  CHEMBL169132 | C33H36F2N2O6S | 626.716 | 10 / 0 | 3.7 | No |
| 131972 |  CHEMBL1083849 | C36H48N4O3S | 616.865 | 6 / 2 | 6.1 | No |
| 133697 |  CHEMBL171541 | C31H33Cl2N3O3 | 566.523 | 4 / 1 | 5.3 | No |
| 138894 |  CHEMBL369246 | C35H41F2N3O6 | 637.725 | 9 / 0 | 4.4 | No |
| 138966 |  CHEMBL171414 | C31H33Cl2N3O4 | 582.522 | 5 / 1 | 4.9 | No |
| 150304 |  CHEMBL243503 | C30H41N5O4S | 567.749 | 6 / 4 | 3.2 | No |
| 150511 |  CHEMBL395975 | C31H37ClN4O4S | 597.171 | 6 / 3 | 4.9 | No |
| 151307 |  CHEMBL229032 | C25H25Cl2N5O7 | 578.403 | 7 / 2 | 4.1 | No |
| 154232 |  CHEMBL302329 | C36H45Cl4N5O5 | 769.586 | 7 / 0 | 5.8 | No |
| 154234 |  CHEMBL60504 | C36H45Cl4N5O5 | 769.586 | 7 / 0 | 5.8 | No |
| 154236 |  CHEMBL66763 | C36H45Cl4N5O5 | 769.586 | 7 / 0 | 5.8 | No |
| 156776 |  CHEMBL1083876 | C35H44N6O2S | 612.837 | 6 / 3 | 5.6 | No |
| 157107 |  CHEMBL1083877 | C34H44N8O2S | 628.84 | 8 / 2 | 5.6 | No |
| 158235 |  CHEMBL366972 | C31H35Cl2N3O6 | 616.536 | 8 / 1 | 4.1 | No |
| 158577 |  CHEMBL184545 | C29H33Cl2N3O2 | 526.502 | 4 / 2 | 5.3 | No |
| 158990 |  CHEMBL1083853 | C35H46N4O3S | 602.838 | 6 / 2 | 6.0 | No |
| 162569 |  CHEMBL1083866 | C36H48N4O3S | 616.865 | 6 / 2 | 6.3 | No |
| 165085 |  CHEMBL360614 | C29H32Cl2N2O2 | 511.487 | 3 / 1 | 5.9 | No |
| 171144 |  CHEMBL1084162 | C34H46N4O4S2 | 638.886 | 7 / 2 | 6.0 | No |
| 171711 |  CHEMBL446086 | C36H47FN4O4 | 618.794 | 6 / 3 | 4.8 | No |
| 175191 |  CHEMBL1083852 | C37H50N4O3S | 630.892 | 6 / 2 | 6.5 | No |
| 175488 |  CHEMBL353394 | C37H43Cl2N3O6 | 696.666 | 7 / 0 | 5.9 | No |
| 176422 |  CHEMBL56739 | C26H34Cl2N2O2 | 477.47 | 3 / 1 | 5.8 | No |
| 177105 |  CHEMBL304106 | C34H43Cl4N5O4 | 727.549 | 6 / 0 | 6.2 | No |
| 177106 |  CHEMBL446146 | C34H43Cl4N5O4 | 727.549 | 6 / 0 | 6.2 | No |
| 177109 |  CHEMBL67171 | C34H43Cl4N5O4 | 727.549 | 6 / 0 | 6.2 | No |
| 177261 |  CHEMBL124208 | C24H26FN3O2 | 407.489 | 4 / 1 | 4.0 | Yes |
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