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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameSubstance-K receptor
SpeciesCavia porcellus (Guinea pig)
GeneTACR2
SynonymNK-2 receptor
Tachykinin receptor 2
Neurokinin A receptor
SKR
NK-2R
DiseaseN/A for non-human GPCRs
Length402
Amino acid sequenceMGACVIVTNTNISSGLESNTTGITAFSMPTWQLALWATAYLALVLVAVTGNATVTWIILAHQRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAIDRYMAIVHPFQPRLSAPSTKAVIGGIWLVALALAFPQCFYSTITEDEGATKCVVAWPEDSRDKSLLLYHLVVIVLIYLLPLTVMFVAYSIIGLTLWRRAVPRHQAHGANLRHLQAKKKFVKTMVLVVVTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNRRFRSGFRLAFRCCPWVTPTEEDKLELTHTPSFSLRVNRCHTKEILFMAGDTVPSEATNGQAGGPQDRESVELSSLPGCRAGPSILAKASS
UniProtQ64077
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2647
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 268
Page:  / 3 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
7612D structureCHEMBL57589C27H34Cl2N2O3505.484 / 05.8No
22532D structureCHEMBL236661C31H40N4O3S548.7465 / 45.3No
24942D structureSubstance PC63H98N18O13S1347.6517 / 15-2.3No
36952D structureCHEMBL242626C36H40N6O4S652.8147 / 34.6No
95702D structureCHEMBL355506C28H29Cl2N5O3554.4726 / 13.2No
109522D structureCHEMBL395972C37H45F3N4O4S698.8469 / 36.6No
133632D structureCHEMBL394607C36H45N5O5S659.8467 / 33.9No
137542D structureCHEMBL352734C29H30Cl2N4O3553.4845 / 14.2No
152422D structureCHEMBL394420C35H38N4O3S594.7745 / 36.0No
175672D structureELEDOISINC54H85N13O15S1188.4117 / 14-3.6No
182482D structureCHEMBL67508C32H39Cl4N5O4699.4956 / 15.6No
182492D structureCHEMBL66635C32H39Cl4N5O4699.4956 / 15.6No
182512D structureCHEMBL441252C32H39Cl4N5O4699.4956 / 15.6No
190212D structureGR-159897C23H27FN2O2S414.5395 / 13.4Yes
236222D structureUNII-G9BL4978MZC27H25Cl2F6N3O3624.4059 / 26.2No
243642D structureCHEMBL354170C32H34Cl2N4O4609.5485 / 24.1No
293492D structureCHEMBL443237C30H31Cl2N3O3552.4964 / 15.0No
359342D structureCHEMBL359587C31H34BrCl2N3O3647.4354 / 25.9No
405372D structureMEN-10627C38H48N8O7S760.9118 / 82.0No
426662D structureCHEMBL171876C31H35Cl2N3O6S648.5968 / 14.6No
448822D structureCHEMBL363727C31H35Cl2N3O3568.5394 / 25.7No
491042D structureCHEMBL353480C33H37Cl2N3O6642.5748 / 05.3No
506232D structureCHEMBL507334C36H47ClN4O4635.2465 / 35.4No
517912D structureCHEMBL231261C29H37Cl2N5O3S606.6075 / 44.5No
527322D structureCHEMBL66106C30H36Cl4N4O3642.4435 / 06.7No
527352D structureCHEMBL68060C30H36Cl4N4O3642.4435 / 06.7No
531662D structureCHEMBL354288C34H39Cl2N3O6656.6017 / 15.2No
544202D structureCHEMBL171725C34H38Cl2N2O6641.5867 / 05.7No
550852D structureCHEMBL301437C26H34Cl2N2O2477.473 / 15.5No
574602D structureCHEMBL237048C36H41N5O3S623.8166 / 35.3No
577312D structureCHEMBL171719C33H36Cl2N2O7S675.6188 / 04.8No
649582D structureCHEMBL172572C29H30Cl2N4O3553.4845 / 13.9No
673942D structureCHEMBL242625C32H39N5O4S589.7556 / 33.5No
698722D structureCHEMBL244364C31H37ClN4O4S597.1716 / 34.9No
699862D structureCHEMBL171704C34H37Cl2N3O6654.5857 / 05.1No
704312D structureCHEMBL1083875C36H44N4O3S612.8336 / 26.5No
721112D structureCHEMBL1083858C35H46N4O3S602.8386 / 26.0No
728722D structureCHEMBL299377C35H41Cl2N3O2606.6323 / 07.0No
735572D structureCHEMBL243725C29H38IN5O4647.5585 / 43.3No
747582D structureCHEMBL354183C33H36Cl2N2O6627.5597 / 05.3No
754632D structureCHEMBL417940C26H32Cl2N2O2475.4543 / 05.4No
782702D structureCHEMBL237097C36H50N4O3S618.8815 / 37.7No
805922D structureCHEMBL397264C33H40N4O4556.7075 / 34.2No
812462D structureCHEMBL170936C35H41Cl2N3O6670.6287 / 05.5No
832782D structureCHEMBL172938C24H28N4O3420.5133 / 43.2Yes
837372D structureCHEMBL1084765C36H48N4O4600.8046 / 25.5No
854382D structureCHEMBL1083855C37H50N4O3S630.8926 / 26.7No
856682D structureCHEMBL1083861C37H48N4O3S628.8766 / 26.1No
882782D structureCHEMBL244566C31H37ClN4O4S597.1716 / 34.9No
910732D structureCHEMBL354756C32H36Cl2N4O6643.5628 / 13.8No
916532D structureCHEMBL355387C33H37FN2O6S608.7259 / 03.6No
924412D structureCHEMBL58331C27H35Cl2N3O2504.4963 / 15.2No
942032D structureCHEMBL424578C32H35Cl2N3O5612.5486 / 14.9No
943612D structureCHEMBL1083880C37H45N5O3S639.8595 / 26.1No
952212D structureCHEMBL1083873C36H44N4O2S2628.8946 / 27.1No
957012D structureCHEMBL171381C31H35Cl2N3O6616.5368 / 14.1No
984712D structureCHEMBL1083864C37H49N3O4S631.8766 / 26.6No
987652D structureCHEMBL169318C29H33Cl2N5O5602.5139 / 04.2No
1000092D structureCHEMBL1083869C38H45FN4O2S640.8626 / 27.5No
1047492D structureCHEMBL184391C29H31Cl2N3O4556.4845 / 15.8No
1063882D structureCHEMBL352615C34H39Cl2N3O7S704.669 / 05.2No
1076762D structureCHEMBL394419C35H38N4O4S610.7736 / 35.2No
1077452D structureCHEMBL244362C36H45BrN4O4S709.7446 / 36.4No
1104432D structureCHEMBL398028C35H38N4O4S610.7736 / 35.1No
1122312D structureCHEMBL1083879C37H48N4O4S644.8756 / 25.7No
1125212D structureNEUROKININ AC50H80N14O14S1133.3318 / 16-4.8No
1125332D structureSubstance KC50H80N14O14S1133.3318 / 16-4.8No
1126062D structureCHEMBL425179C30H31Cl2N3O2S568.5575 / 17.3No
1137362D structureCHEMBL353596C33H37ClN2O6S625.1778 / 04.2No
1147952D structureCHEMBL1083863C38H51N3O3S629.9045 / 28.0No
1231412D structureCHEMBL395971C36H45FN4O4S648.8387 / 35.8No
1268752D structureCHEMBL1083868C35H42N6O2S610.8217 / 26.3No
1291262D structureGR100679C34H44N6O5616.7635 / 53.4No
1318462D structureCHEMBL169132C33H36F2N2O6S626.71610 / 03.7No
1319722D structureCHEMBL1083849C36H48N4O3S616.8656 / 26.1No
1336972D structureCHEMBL171541C31H33Cl2N3O3566.5234 / 15.3No
1388942D structureCHEMBL369246C35H41F2N3O6637.7259 / 04.4No
1389662D structureCHEMBL171414C31H33Cl2N3O4582.5225 / 14.9No
1503042D structureCHEMBL243503C30H41N5O4S567.7496 / 43.2No
1505112D structureCHEMBL395975C31H37ClN4O4S597.1716 / 34.9No
1513072D structureCHEMBL229032C25H25Cl2N5O7578.4037 / 24.1No
1542322D structureCHEMBL302329C36H45Cl4N5O5769.5867 / 05.8No
1542342D structureCHEMBL60504C36H45Cl4N5O5769.5867 / 05.8No
1542362D structureCHEMBL66763C36H45Cl4N5O5769.5867 / 05.8No
1567762D structureCHEMBL1083876C35H44N6O2S612.8376 / 35.6No
1571072D structureCHEMBL1083877C34H44N8O2S628.848 / 25.6No
1582352D structureCHEMBL366972C31H35Cl2N3O6616.5368 / 14.1No
1585772D structureCHEMBL184545C29H33Cl2N3O2526.5024 / 25.3No
1589902D structureCHEMBL1083853C35H46N4O3S602.8386 / 26.0No
1625692D structureCHEMBL1083866C36H48N4O3S616.8656 / 26.3No
1650852D structureCHEMBL360614C29H32Cl2N2O2511.4873 / 15.9No
1711442D structureCHEMBL1084162C34H46N4O4S2638.8867 / 26.0No
1717112D structureCHEMBL446086C36H47FN4O4618.7946 / 34.8No
1751912D structureCHEMBL1083852C37H50N4O3S630.8926 / 26.5No
1754882D structureCHEMBL353394C37H43Cl2N3O6696.6667 / 05.9No
1764222D structureCHEMBL56739C26H34Cl2N2O2477.473 / 15.8No
1771052D structureCHEMBL304106C34H43Cl4N5O4727.5496 / 06.2No
1771062D structureCHEMBL446146C34H43Cl4N5O4727.5496 / 06.2No
1771092D structureCHEMBL67171C34H43Cl4N5O4727.5496 / 06.2No
1772612D structureCHEMBL124208C24H26FN3O2407.4894 / 14.0Yes

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