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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameGlucose-dependent insulinotropic receptor
SpeciesRattus norvegicus (Rat)
GeneGpr119
SynonymGPCR2
glucose-dependent insulinotropic receptor
G-protein coupled receptor 2
G-protein coupled receptor 119
G protein-coupled receptor 119
[ Show all ]
DiseaseN/A for non-human GPCRs
Length468
Amino acid sequenceMESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGGCIAGLWLISYLIGFLPLGVSIFQQTTYHGPCTFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQHIRKMEHAGAMVGACRPPRPVNDFKAVRTVSVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLCHMALGLLADGSTQPQIETLKGKEERKKVGRKTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDACDTQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDTQTLYTCDAQTLYTCDAQTLYTCDAQTLYTCDAQTLYTSSLVTGQTEQTPLKRANMSDPLRTCRG
UniProtQ7TQN8
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5262
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 89
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
4417122D structureCHEMBL3326687C22H24F2N6O6S538.52713 / 02.4No
57112D structureCHEMBL1773288C23H29N5O5S487.5758 / 03.2Yes
61642D structureCHEMBL1775177C22H28N6O5S488.5639 / 01.9Yes
102162D structureCHEMBL1775175C22H25N5O6S487.5319 / 01.9Yes
114152D structureCHEMBL1951033C22H31N5O6S493.57910 / 12.9Yes
4422042D structureCHEMBL3325849C19H22F2N4O6S472.46411 / 02.7No
142952D structureCHEMBL1951015C20H27N5O3385.4687 / 13.3Yes
168302D structureCHEMBL1773292C22H26FN5O6S507.5379 / 12.0No
175992D structureCHEMBL1775170C20H23N5O5S445.4948 / 02.2Yes
4426812D structureCHEMBL3325850C20H24F2N4O6S486.49111 / 02.6No
4426822D structureCHEMBL3325851C20H24F2N4O6S486.49111 / 02.6No
4428352D structureCHEMBL3326689C21H20ClFN6O5S522.93611 / 02.3No
327192D structureCHEMBL1951022C21H29N5O5S463.5539 / 12.9Yes
328162D structureCHEMBL1773290C22H27N5O5S473.5488 / 02.7Yes
4430582D structureCHEMBL3326685C22H25FN6O6S520.53612 / 02.8No
402312D structureCHEMBL1951012C21H27FN4O5S466.5289 / 13.3Yes
4433042D structureCHEMBL3326673C21H27FN4O5S2498.58810 / 03.4Yes
530852D structureCHEMBL1949674C21H28N4O4400.4797 / 03.7Yes
541222D structureCHEMBL1775173C22H27N5O5S473.5488 / 03.2Yes
4438902D structureCHEMBL3325846C21H24F4N4O6S536.49913 / 03.6No
590992D structure733750-99-7C21H24FN7O5S505.52512 / 13.9No
602602D structureCHEMBL1775174C23H27N5O5S485.5598 / 03.1Yes
4440842D structureCHEMBL3326672C20H25FN4O5S2484.56110 / 03.2Yes
693362D structureCHEMBL1773287C23H28FN5O4S489.5668 / 03.1Yes
760682D structureCHEMBL1775178C22H26FN5O5S491.5389 / 02.9Yes
762042D structureCHEMBL1951011C21H26FN3O6S467.5129 / 03.3Yes
904422D structureCHEMBL1951025C21H29N5O5S463.5539 / 12.9Yes
4454142D structureCHEMBL3326680C19H21F3N4O5S474.45511 / 02.5No
4458162D structureCHEMBL3326674C20H23FN4O5S2482.54510 / 02.9Yes
1128542D structureCHEMBL1951028C22H31N5O5S477.589 / 13.3Yes
4463102D structureCHEMBL3325461C20H24F2N4O5S470.49210 / 02.4Yes
1241972D structureCHEMBL1773294C21H24N4O6S460.5059 / 02.5Yes
4466862D structureCHEMBL3325844C21H27FN4O6S482.52710 / 02.8Yes
1314172D structureCHEMBL1951021C21H28N4O6S464.5379 / 02.9Yes
4471882D structureCHEMBL3326669C20H23FN4O7S482.48311 / 01.5No
4472712D structureCHEMBL3326676C21H25FN4O5S2496.57210 / 03.3Yes
1438252D structureCHEMBL1951016C19H25N5O3371.4417 / 12.9Yes
4474142D structureCHEMBL3325843C20H25FN4O6S468.510 / 02.6Yes
1488382D structureCHEMBL1773289C24H31N5O5S501.6028 / 03.6No
4480502D structureCHEMBL3326681C20H23F3N4O5S488.48211 / 03.0No
1633132D structureCHEMBL1773293C22H26N4O6S474.5329 / 02.7Yes
4481132D structureCHEMBL3325847C21H24FN5O6S493.5111 / 02.2No
4481402D structureCHEMBL3326678C21H25FN4O5S2496.57210 / 03.2Yes
1761252D structureCHEMBL1773283C22H26FN5O4S2507.5999 / 03.5No
1792242D structureCHEMBL1951013C21H29N5O5S463.5539 / 12.9Yes
4489462D structureCHEMBL3325852C20H22F4N4O6S522.47213 / 03.4No
4489492D structureCHEMBL3326666C20H22F4N4O6S522.47213 / 03.4No
1876952D structureCHEMBL1773286C23H29N5O4S471.5767 / 03.0Yes
1984412D structureCHEMBL1951019C20H23N5O4397.4358 / 02.6Yes
1999062D structureCHEMBL1775169C22H27N5O5S473.5488 / 02.8Yes
2172252D structureCHEMBL1951020C21H28N4O5416.4788 / 03.6Yes
2201302D structureCHEMBL1773285C22H27N5O6S2521.6079 / 02.1No
2301982D structureCHEMBL1775172C22H27N5O5S473.5488 / 03.1Yes
2370142D structureCHEMBL1773277C22H28N6O4S472.5648 / 12.8Yes
4513262D structureCHEMBL3326677C20H25FN4O5S2484.56110 / 03.2Yes
2527532D structureCHEMBL1951024C21H28N4O6S464.5379 / 02.9Yes
4521352D structureCHEMBL3326671C21H22F4N4O7S550.48214 / 02.5No
4521392D structureCHEMBL3326675C21H25FN4O5S2496.57210 / 03.1Yes
2696702D structureCHEMBL1949688C19H24N6O7S480.49611 / 12.9No
4526242D structureCHEMBL3326668C22H27FN4O6S494.53810 / 03.1Yes
2822102D structureCHEMBL1773279C24H32N6O4S500.6188 / 03.2No
2906062D structureCHEMBL1775176C23H29N5O5S487.5758 / 03.6Yes
2932562D structureCHEMBL1766082C22H28N4O5428.4898 / 02.7Yes
4534362D structureCHEMBL3326688C23H25FN6O5S516.54811 / 02.5No
3008832D structureCHEMBL1773291C21H26N6O5S474.5369 / 02.4Yes
3128732D structureCHEMBL1951017C20H26N4O4386.4527 / 03.3Yes
4547232D structureCHEMBL3325842C20H26FN5O5S467.51610 / 12.6Yes
4547532D structureCHEMBL3325848C21H26F2N4O6S500.51811 / 02.8No
3287192D structureCHEMBL1773282C22H27N5O4S2489.6098 / 03.4Yes
4548542D structureCHEMBL3326667C21H25FN4O6S480.51110 / 02.6Yes
4553902D structureCHEMBL3326682C21H24F2N4O5S482.50310 / 02.5Yes
3454382D structureCHEMBL1773281C24H31FN6O4S518.6089 / 03.5No
3573232D structureCHEMBL1773280C25H34N6O4S514.6458 / 03.5No
3628372D structureCHEMBL1951014C21H29N5O5S463.5539 / 12.9Yes
3710072D structureCHEMBL1951023C20H27N5O5S449.5269 / 12.5Yes
4564702D structureCHEMBL3325845C21H25FN4O6S480.51110 / 02.7Yes
3768082D structureCHEMBL1775171C21H25N5O5S459.5218 / 02.6Yes
3789242D structureAPD597C21H29N5O6S479.55210 / 12.5Yes
4569712D structureCHEMBL3326670C22H24F4N4O6S548.5113 / 03.7No
4570662D structureCHEMBL3326686C22H24F2N6O6S538.52713 / 02.4No
3911012D structureCHEMBL1773284C22H27N5O5S2505.6089 / 01.9No
4006572D structureAPD668C21H24FN5O5S477.5119 / 02.7Yes
4577442D structureCHEMBL3326683C22H27FN4O5S478.5399 / 03.0Yes
4102992D structureCHEMBL1766081C20H26N4O4386.4527 / 03.3Yes
4585822D structureCHEMBL3326679C18H18F4N4O5S478.41912 / 02.5No
4312652D structureCHEMBL1773278C23H30N6O4S486.5918 / 13.0Yes
4325382D structureCHEMBL3104879C23H19ClFN3O5S503.9298 / 14.1No
4380302D structureCHEMBL1951018C19H23FN4O4390.4158 / 03.0Yes
4382322D structureCHEMBL1951026C20H26N4O4386.4527 / 03.3Yes

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