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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameGlucose-dependent insulinotropic receptor
SpeciesMus musculus (Mouse)
GeneGpr119
SynonymG-protein coupled receptor 119
G protein-coupled receptor 119
G-protein coupled receptor 2
glucose-dependent insulinotropic receptor
GPCR2
[ Show all ]
DiseaseN/A for non-human GPCRs
Length335
Amino acid sequenceMESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKFFTSILLLLPARNRGPERTRESAYHIVTISHPELDG
UniProtQ7TQP3
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5263
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 245
Page:  / 3 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
1522D structureCHEMBL2058674C22H30N4O2382.5086 / 14.6Yes
88852D structureCHEMBL2086689C20H19FN8O406.42510 / 01.5Yes
4420662D structureCHEMBL3354776C26H24F3N3O2467.4927 / 05.8No
4421432D structureCHEMBL3358010C23H26F4N4O6S562.53713 / 02.1No
4421502D structureCHEMBL3354805C25H21F4N5O483.4719 / 22.6Yes
126782D structureCID 62707005C21H28N4O2S400.5417 / 15.1No
4422582D structureCHEMBL3358000C20H18F4N10O2506.42615 / 02.6No
165582D structureCHEMBL2086686C21H23N7O3421.4619 / 01.3Yes
184412D structureCHEMBL2010836C23H25F3N6O458.4898 / 03.6Yes
186122D structureCHEMBL1771084C21H28N4O2S400.5416 / 02.8Yes
207832D structureCHEMBL3220233C22H24N8O4464.48612 / 00.7No
220282D structureCHEMBL1777817C22H28N4O4412.497 / 03.9Yes
4425852D structureCHEMBL3354781C27H24F3N3O2479.5037 / 05.8No
245772D structureCHEMBL1778247C22H24FN5O3S457.5249 / 13.6Yes
250112D structureCHEMBL2382408C23H30N4O5S474.5768 / 02.6Yes
4662432D structureCHEMBL3622172C23H30FN3O4S463.5688 / 02.4Yes
5224362D structuren-oleoylethanolamineC20H39NO2325.5372 / 26.3No
4673812D structureCHEMBL3629479C24H31ClN4O6S539.0449 / 13.8No
380272D structureCHEMBL2086655C22H29N3O5S447.557 / 02.7Yes
4432352D structureCHEMBL3358004C21H23F4N7O3S529.51514 / 13.8No
4434632D structureCHEMBL3358007C21H22F4N6O3S514.514 / 02.8No
456342D structureCHEMBL1771098C24H28ClFN4O2458.9626 / 14.8Yes
480632D structureCHEMBL1771088C22H28ClN3O2S433.9955 / 04.5Yes
485012D structureCHEMBL1771093C20H24ClN7397.9117 / 03.7Yes
492722D structureCHEMBL1770918C20H31N3O2345.4874 / 03.4Yes
4689942D structureCHEMBL3622177C24H32FN3O4S477.5958 / 02.8Yes
4693882D structureCHEMBL3622167C22H30FN3O4S451.5578 / 03.8Yes
4438152D structureCHEMBL3354790C24H18F3N3O3453.4218 / 04.0Yes
537192D structureCHEMBL2058391C21H32N2O4S408.5575 / 13.5Yes
554982D structureCHEMBL2086658C22H29N3O5S447.557 / 02.4Yes
574422D structureCHEMBL1771065C22H34N2O2358.5263 / 04.8Yes
575722D structureCHEMBL3220238C23H28N6O4452.5159 / 01.7Yes
577412D structureCHEMBL1778150C21H26N4O4S430.5238 / 03.1Yes
583502D structureCHEMBL2382412C21H20F4N6O3480.42412 / 02.4No
585642D structureCHEMBL2058397C19H30N4O4S410.5337 / 33.2Yes
590982D structure733750-99-7C21H24FN7O5S505.52512 / 13.9No
604272D structureCHEMBL1771083C22H29N3O2S399.5535 / 03.9Yes
4441292D structureCHEMBL3357999C20H17F4N7O2463.39713 / 03.1No
4706992D structureCHEMBL3629597C24H26FN5O5483.510 / 12.8Yes
633422D structureCHEMBL2058673C23H30N4O378.525 / 14.3Yes
651502D structureCHEMBL1771069C22H34N2O4S422.5845 / 03.7Yes
730302D structureCID 62706519C21H30N2O4374.4815 / 13.8Yes
758492D structureCHEMBL1778145C24H30N4O4438.5287 / 04.3Yes
800212D structureCHEMBL1771064C21H32N2O2344.4993 / 04.4Yes
837492D structureCHEMBL1778151C21H28N4O4S432.5398 / 03.4Yes
913222D structureCHEMBL2087084C21H24N8O2420.47710 / 02.5Yes
937782D structureCHEMBL2058405C22H32N2O4388.5085 / 13.7Yes
953572D structureSCHEMBL1447845C21H21F3N6O4478.43212 / 01.5No
4455192D structureCHEMBL3358012C22H24F4N4O6S548.5113 / 02.2No
4456092D structureCHEMBL3354804C26H22F4N4O482.4838 / 23.6Yes
1015902D structureCHEMBL1771095C21H27N7377.4967 / 03.0Yes
1033682D structureCHEMBL2086668C21H35N5O5S469.6019 / 01.8Yes
1084202D structureCHEMBL2086675C19H25N5O3371.4417 / 01.7Yes
4460992D structureCHEMBL3358014C22H27FN6O4S490.55411 / 03.2No
1123932D structureCHEMBL2058398C22H32N2O3372.5094 / 14.0Yes
4461872D structureCHEMBL3358013C23H29FN6O4S504.58111 / 03.1No
1146682D structureCHEMBL1771099C24H28ClFN4O2458.9626 / 14.8Yes
1169322D structureCHEMBL2086666C22H28N4O5S460.5498 / 02.3Yes
4774402D structureCHEMBL3622174C23H30FN3O3S447.5697 / 03.5Yes
1234902D structureCHEMBL3220240C21H24N6O4424.4619 / 00.8Yes
1257342D structureCHEMBL2382410C22H26N6O3422.4898 / 02.1Yes
4466492D structureCHEMBL3358006C21H22F4N6O4S530.49914 / 02.9No
4468192D structureCHEMBL3354780C25H19F4N3O2469.448 / 05.0Yes
4468312D structureCHEMBL3357998C21H23F3N6O4S512.50813 / 02.4No
1376892D structureCHEMBL3260506C23H18Cl2FN3O2458.3145 / 05.5No
1387462D structureCHEMBL2086693C19H17F3N8O2446.39413 / 02.3No
1405412D structureCID 62706851C22H26N4O4410.4748 / 13.2Yes
1418452D structureCHEMBL2086650C21H28N4O5S448.5388 / 02.0Yes
4473792D structureCHEMBL3358001C21H22F4N6O4S530.49914 / 02.5No
1458772D structureCHEMBL3217767C21H24N8O2420.47710 / 02.1Yes
1486332D structureCHEMBL1778144C23H28N4O4424.5017 / 03.9Yes
1489832D structureCHEMBL1778253C21H25FN4O4S448.5139 / 03.1Yes
1490842D structureCHEMBL1778152C21H25F3N4O4S486.5111 / 04.0No
1534562D structureCHEMBL1778239C24H25FN4O4S484.5469 / 04.2Yes
4819072D structureCHEMBL3629596C23H24ClN5O4469.9268 / 13.4Yes
1545082D structureCHEMBL2086685C20H24N6O3396.4518 / 01.7Yes
1548022D structureCHEMBL3220244C20H22N6O4410.4349 / 00.6Yes
1560542D structurecompound 36jC22H24ClN5O3S473.9768 / 14.1Yes
1572392D structureCID 62706850C21H26N4O3382.4647 / 13.3Yes
1574962D structureBDBM50387903C21H30N2O4374.4815 / 24.3Yes
1602212D structureCHEMBL2087085C21H22N8O2418.46110 / 01.9Yes
1608652D structureCHEMBL2087086C19H17F3N8O2446.39413 / 02.3No
4828532D structureCHEMBL3629598C22H24ClN5O4S489.9759 / 13.2Yes
1623692D structureCHEMBL2086677C20H27N5O3385.4687 / 02.1Yes
1659112D structureCHEMBL1778251C21H24N4O4S428.5078 / 02.8Yes
1659652D structureCHEMBL1778241C21H24ClN3O4S449.957 / 04.4Yes
1666182D structureCHEMBL3260540C24H21F3N4O2454.4538 / 04.4Yes
1667052D structureSCHEMBL1447914C22H24N8O3448.48711 / 01.6No
1685412D structureCHEMBL2086672C22H29FN4O5S480.5559 / 02.6Yes
4484452D structureCHEMBL3354803C25H19F4N5O3513.45310 / 23.0No
4843112D structure2-(4-((1R,2R)-2-(((2-fluoro-4-(methylsulfonyl)benzyl)oxy)methyl)cyclopropyl)piperidin-1-yl)-5-(methoxymethyl)pyrimidineC23H30FN3O4S463.5688 / 02.4Yes
1732502D structureCHEMBL1771081C21H31N5O2385.5126 / 03.5Yes
1734732D structureCHEMBL2086679C19H24FN5O3389.4318 / 01.8Yes
4851052D structureCHEMBL3629478C24H28ClN5O4485.9698 / 14.3Yes
4487642D structureCHEMBL3354774C26H24F3N3O2467.4927 / 05.7No
4852232D structureCHEMBL3622169C22H28FN5O3429.4967 / 03.0Yes
1862692D structureCHEMBL2058406C21H31N3O3373.4974 / 23.1Yes
1910582D structureCHEMBL2086659C22H30N4O5S462.5658 / 02.5Yes
1910612D structureCHEMBL2086660C22H30N4O5S462.5658 / 02.5Yes
1919712D structureCHEMBL1771103C21H26N6O378.487 / 03.7Yes

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