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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameKiSS-1 receptor
SpeciesHomo sapiens (Human)
GeneKISS1R
SynonymMetastin receptor
Kisspeptins receptor
kisspeptin receptor
KiSS1-derived peptide receptor
KiSS-1R
[ Show all ]
DiseaseProstate cancer
Length398
Amino acid sequenceMHTVATSGPNASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLSPGPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRRPRRPRRPGPSDPAAPHAELLRLGSHPAPARAQKPGSSGLAARGLCVLGEDNAPL
UniProtQ969F8
Protein Data BankN/A
GPCR-HGmod modelQ969F8
3D structure modelThis predicted structure model is from GPCR-EXP Q969F8.
BioLiPN/A
Therapeutic Target DatabaseT39123
ChEMBLCHEMBL5413
IUPHAR266
DrugBankN/A

Known ligands

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Total entries: 293
Page:  / 3 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
2252D structureBDBM50203786C75H105N23O181616.8121 / 22-4.4No
5132D structureCHEMBL3085807C60H88N18O131269.4816 / 17-1.1No
4417152D structureCHEMBL3314214C60H79N17O121230.415 / 16-0.3No
20282D structureBDBM50203804C75H110N24O181635.8521 / 23-5.7No
23532D structureCHEMBL385105C75H100N18O181541.7319 / 19-1.7No
52642D structureCHEMBL268659C40H51N11O6781.9198 / 91.2No
5360772D structureCHEMBL3928465C64H82FN17O131316.4615 / 181.3No
71542D structureCHEMBL2152060C64H85N17O141316.4916 / 18-1.5No
99112D structureCHEMBL218690C30H23N5O2S517.6075 / 24.4No
5576232D structureCHEMBL1171102C28H22FN5O4511.5138 / 44.0No
5480242D structureCHEMBL3982675C59H82N16O131223.414 / 16-0.3No
145302D structureCHEMBL440431C44H57N11O7852.018 / 101.4No
149192D structureCHEMBL229621C43H57N13O6852.0148 / 110.7No
149292D structureLPNYNWNSFGLRFC78H106N20O191627.8321 / 21-4.5No
5576942D structureCHEMBL1171104C29H26FN5O4527.5568 / 44.8No
155152D structureCHEMBL373854C82H106N18O181631.8619 / 190.3No
4425012D structureCHEMBL3314224C64H83N17O131298.4714 / 181.2No
5481262D structureCHEMBL3985112C64H83N17O131298.4714 / 181.2No
211872D structureCHEMBL226537C41H52N10O9828.92810 / 121.2No
254922D structureCHEMBL388146C41H51N11O8825.9289 / 92.1No
5367132D structureCHEMBL3977314C58H79FN16O151259.3617 / 18-1.0No
4428252D structureCHEMBL3314227C69H85N17O131360.5514 / 193.1No
5581692D structureCHEMBL1163808C31H29N5O4535.6047 / 44.1No
5582792D structureCHEMBL1171296C30H26FN5O4539.5678 / 34.8No
4429562D structureCHEMBL3422510C69H93N17O161416.6117 / 20-0.1No
347142D structureCHEMBL221764C78H106N20O191627.8320 / 21-2.6No
4430452D structureCHEMBL3422010C21H19N5OS2421.5376 / 03.0Yes
5583612D structureCHEMBL1171797C32H32FN5O4569.6378 / 35.6No
357582D structureCID 44419669C78H107N21O181626.8420 / 22-2.2No
361772D structureBDBM50203780C75H101N21O181584.7620 / 21-4.2No
368342D structureCHEMBL2151645C64H85N17O141316.4916 / 18-1.2No
4431612D structureCHEMBL3422516C89H128N20O181766.1221 / 216.5No
5369522D structureCHEMBL3939287C55H75FN16O131187.315 / 17-0.9No
5369842D structureCHEMBL3985323C56H78N16O131183.3414 / 17-1.1No
4432442D structureCHEMBL3422407C65H85N17O161360.517 / 20-1.9No
403522D structureCHEMBL3087930C56H81N17O151232.3717 / 19-3.8No
403532D structureCHEMBL2151648C56H81N17O151232.3717 / 19-3.8No
5585402D structureCHEMBL1165103C27H23N5O4S513.5728 / 43.9No
5370912D structureCHEMBL3931718C57H78N16O131195.3514 / 16-1.1No
434642D structureCHEMBL3645505C10H20N2O2200.2823 / 20.6Yes
434652D structureCHEMBL3645498C10H20N2O2200.2823 / 20.6Yes
435202D structureBDBM50203814C79H109N21O181640.8720 / 21-2.1No
4435762D structureCHEMBL3314225C66H87N17O131326.5314 / 182.0No
493722D structureCHEMBL388586C41H51FN10O6798.9218 / 92.4No
493752D structurePeptide analogue, 26C41H51FN10O6798.9218 / 92.4No
568722D structureCHEMBL389708C41H52N10O7796.938 / 101.9No
4440232D structureCHEMBL3422511C70H94N18O161443.6317 / 20-0.8No
4440652D structureCHEMBL3422018C20H18N6OS2422.5257 / 02.8Yes
623212D structureCHEMBL2151651C60H82N18O141279.4317 / 18-2.6No
4442032D structureCHEMBL3422410C67H85N21O141408.5519 / 18-1.5No
5593312D structureCHEMBL1169893C27H23N5O3S497.5737 / 34.5Yes
5594412D structureCHEMBL1164988C26H20ClN5O3S517.9887 / 44.6No
4444462D structureCHEMBL3314217C63H83N17O111254.4613 / 172.5No
711102D structureUS8592379, 37C11H23NO2201.313 / 20.9Yes
711112D structureUS8592379, 35C11H23NO2201.313 / 20.9Yes
718762D structureCHEMBL389262C40H59N11O6789.9838 / 100.7No
4446012D structureCHEMBL3314209C60H81N17O111216.4214 / 161.3No
787302D structureCID 44419652C74H106N22O191607.821 / 23-5.3No
4449232D structureCHEMBL3422413C69H93N17O161416.6117 / 20-0.1No
817792D structureCHEMBL223390C42H54N10O7810.9578 / 92.2No
5598772D structureCHEMBL1165432C29H26FN5O4527.5568 / 44.2No
5598972D structureCHEMBL1164939C27H23N5O3S497.5737 / 43.8Yes
5489392D structureCHEMBL3964403C63H82N16O131271.4514 / 160.8No
5600742D structureCHEMBL1164673C24H18N4O2S426.4946 / 34.1Yes
918572D structureCHEMBL268579C40H51N11O6781.9198 / 91.5No
920042D structureCHEMBL2152063C63H83N17O141302.4616 / 18-1.8No
923542D structureCHEMBL375432C78H107N19O181598.8320 / 20-1.9No
5489902D structureCHEMBL3976038C59H84N16O131225.4214 / 170.8No
928012D structureCHEMBL388585C41H51ClN10O6815.3737 / 92.9No
931562D structureCHEMBL415004C42H54N10O7810.9578 / 101.4No
931612D structurePeptide analogue, 24aC42H54FN9O6799.9498 / 93.0No
931622D structurePeptide analogue, 25bC42H54FN9O6799.9498 / 93.0No
931632D structurePeptide analogue, 24bC42H54FN9O6799.9498 / 93.0No
931642D structurePeptide analogue, 25aC42H54FN9O6799.9498 / 93.0No
4455032D structureCHEMBL3314221C61H80N16O111213.4113 / 172.4No
4455222D structureCHEMBL3314220C60H78N16O111199.3913 / 172.0No
5603212D structureCHEMBL1163739C27H23N5O4481.5127 / 43.7Yes
998592D structureBDBM50392498C63H82N18O151331.4617 / 19-3.1No
5178462D structureCHEMBL3926886C11H21NO183.2952 / 11.8Yes
4456342D structureCHEMBL3314218C57H76N16O111161.3414 / 160.8No
1009812D structureCHEMBL2152062C62H81N17O141288.4416 / 18-2.4No
4457472D structureCHEMBL3314219C58H78N16O121191.3615 / 170.2No
5605062D structureCHEMBL1171483C28H25ClFN5O4549.9878 / 4N/ANo
1034832D structureCHEMBL2151646C63H84N18O141317.4816 / 19-1.4No
1034852D structureCHEMBL2151654C63H84N18O141317.4816 / 19-1.4No
1034872D structureCHEMBL3085804C63H84N18O141317.4816 / 19-1.4No
1034902D structureCHEMBL3087925C63H84N18O141317.4816 / 19-1.4No
1036112D structureCHEMBL2152052C63H83N15O141274.4516 / 17-1.1No
1077262D structureCHEMBL387648C49H61N11O6900.0988 / 103.1No
1096632D structureCHEMBL3645500C11H23NO185.3112 / 11.9Yes
5608222D structureCHEMBL1170894C29H26FN5O4527.5568 / 34.3No
1161802D structureCHEMBL2152067C62H80N16O151289.4217 / 18-2.6No
5609272D structureCHEMBL1172940C28H24FN5O3497.538 / 24.7Yes
1224822D structureCHEMBL2152054C62H81N15O141260.4216 / 17-1.4No
1226342D structureCHEMBL226566C41H52N10O7796.938 / 101.9No
1235192D structureCHEMBL2152066C60H77N15O141232.3716 / 17-2.1No
4465962D structureCHEMBL3422406C63H83N17O151318.4617 / 19-2.4No
5612392D structureCHEMBL1171977C27H22FN5O4499.5028 / 34.0Yes
5612542D structureCHEMBL1163888C27H23N5O3S497.5737 / 44.3Yes
1284702D structureCID 44419665C69H106N24O181559.7621 / 25-6.5No

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