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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameProteinase-activated receptor 4
SpeciesHomo sapiens (Human)
GeneF2RL3
Synonymprotease-activated receptor 4
PAR4
PAR-4
F2R like thrombin/trypsin receptor 3
coagulation factor II receptor-like 3
[ Show all ]
DiseaseN/A
Length385
Amino acid sequenceMWGRLLLWPLVLGFSLSGGTQTPSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFLPLLAMLLCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSLLQ
UniProtQ96RI0
Protein Data BankN/A
GPCR-HGmod modelQ96RI0
3D structure modelThis predicted structure model is from GPCR-EXP Q96RI0.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4691
IUPHAR350
DrugBankN/A

Known ligands

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Total entries: 916
Page:  / 10 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5214402D structureCHEMBL3715600C25H20N4O5S2520.57810 / 05.4No
5214462D structureCHEMBL3717785C23H14Cl2N4O3S2529.418 / 06.7No
5214922D structureCHEMBL3731529C13H10N4OS2302.376 / 03.7Yes
5215172D structureCHEMBL3731454C13H9N3O3S287.2936 / 12.9Yes
5215192D structureCHEMBL3731621C19H14N4O2S2394.4677 / 04.7Yes
5215392D structureCHEMBL3715726C28H23ClN4O5S2595.08510 / 06.1No
5215652D structureCHEMBL3717630C29H25FN4O5S2592.6611 / 06.0No
5215672D structureCHEMBL3719349C27H19N5O4S509.549 / 05.0No
5216582D structureCHEMBL3717407C27H19F3N4O4S552.52811 / 06.2No
5216782D structureCHEMBL3733083C21H15F2N3O2S411.4277 / 05.3No
5217262D structureCHEMBL3728707C28H21F2N3O5S549.54910 / 07.1No
5217292D structure2-methoxy-6-(6-methoxy-4-((6-(4-methoxytetrahydro-2H-pyran-4-yl)pyridin-2-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazoleC26H26N4O6S522.57610 / 03.5No
5217432D structureCHEMBL3731418C21H16FN3O2S393.4366 / 05.0Yes
5218072D structureCHEMBL3715416C26H19FN4O4S502.529 / 05.4No
5218222D structureCHEMBL3730335C14H8ClF2N3OS339.7456 / 04.5Yes
5218312D structureCHEMBL3732593C28H21Cl2N3O5S582.4528 / 07.4No
5218382D structureCHEMBL3728411C13H9F2N5OS321.3068 / 12.5Yes
5218542D structureCHEMBL3727624C16H16N4O2S328.396 / 04.1Yes
5218772D structureCHEMBL3731003C24H28N4O6S500.579 / 04.6No
5218782D structureCHEMBL3731346C24H28N4O6S500.579 / 04.6No
5218822D structureCHEMBL3730373C11H4BrFN4S2355.2036 / 04.1Yes
5218872D structureCHEMBL3715516C25H20N4O6S3568.63711 / 04.7No
5219052D structureCHEMBL3731476C28H21N3O6S527.5519 / 06.1No
5219182D structureCHEMBL3732437C28H24N4O5S528.5839 / 05.5No
5219652D structureCHEMBL3717638C26H20N4O6S2548.58811 / 05.3No
5219992D structureCHEMBL3732006C20H16N4O3S2424.4938 / 04.7Yes
5220052D structureCHEMBL3719195C26H20FN5O4S2549.59510 / 05.0No
5220252D structureCHEMBL3716844C30H27N5O6S2617.69511 / 14.4No
5220372D structureCHEMBL3732453C14H10BrN3OS348.2184 / 04.7Yes
5220432D structureCHEMBL3717974C33H33N5O5S2643.77710 / 06.9No
5220512D structureCHEMBL3717068C25H17F3N4O4S2558.5512 / 06.3No
5220612D structureCHEMBL3731836C35H28N4O6S632.6919 / 17.0No
5220892D structureCHEMBL3715995C24H22F3N5O6S3629.64415 / 04.8No
5221012D structureCHEMBL3727627C12H7ClN4S3338.8466 / 04.5Yes
5222132D structureCHEMBL3718074C31H29N5O5S2615.72310 / 06.0No
5222152D structure(S)-4-(6-(((2-(2-(1-fluoroethyl)imidazo[2,1-b][1,3,4]thiadiazol-6-yl)-6-methoxybenzofuran-4-yl)oxy)methyl)pyridin-2-yl)tetrahydro-2H-pyran-4-olC26H25FN4O5S524.56710 / 13.3No
5222182D structureCHEMBL3717354C23H21F2N5O4S2533.56912 / 05.4No
5222242D structureCHEMBL3719375C31H28N4O7S2632.70612 / 05.7No
5222342D structureCHEMBL3730076C20H15ClN4O2S410.8766 / 05.3No
5222412D structureCHEMBL3731032C13H7Cl2N3O2S340.1785 / 04.5Yes
5222982D structureCHEMBL3727531C30H27N3O7S573.6210 / 06.1No
5223232D structureCHEMBL3717746C24H19N5O4S2505.56710 / 04.7No
5223322D structureCHEMBL3718860C25H20N4O4S2504.5799 / 05.8No
5223522D structureCHEMBL3719253C29H27N5O5S2589.68510 / 05.7No
4426952D structureCHEMBL3334943C19H20N2O4340.3794 / 03.0Yes
5223752D structure(2-(3-(((6-Methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzofuran-4-yl)oxy)methyl)phenyl)-5-methylthiazol-4-yl)methanolC26H22N4O5S2534.60510 / 14.9No
5223912D structureCHEMBL3717348C31H29N5O5S2615.72310 / 06.1No
5224192D structureCHEMBL3732891C13H8ClN3O2S305.7365 / 03.9Yes
5224372D structureCHEMBL3716704C25H21N5O4S487.5348 / 04.6Yes
5224402D structureCHEMBL3719217C28H22F3N5O5S2629.62913 / 16.2No
5224742D structureCHEMBL3732045C27H21N3O5S499.5418 / 15.8No
5224812D structureCHEMBL3717427C26H27N5O4S505.5939 / 04.3No
5225072D structureCHEMBL3730410C36H31N3O5S617.728 / 08.4No
5225272D structureCHEMBL3732636C21H17N3O3S2423.5057 / 05.2No
4429762D structureCHEMBL3334899C24H21F3N2O4S490.4978 / 13.7Yes
5225632D structureCHEMBL3717332C26H26N4O6S2554.63611 / 04.5No
5225652D structureCHEMBL3731424C13H9N3O2S2303.3546 / 13.4Yes
5225772D structureCHEMBL3716464C23H18N6O4S2506.55511 / 04.1No
5225792D structureCHEMBL3732785C28H21F2N3O5S549.54910 / 06.4No
5225822D structureCHEMBL3715066C23H22N4O4S2482.5739 / 05.5No
5225852D structureCHEMBL3730242C13H8FN3OS2305.3456 / 03.9Yes
5225982D structureCHEMBL3729754C15H11F2N3OS319.336 / 04.2Yes
5226002D structureCHEMBL3730143C14H10ClN3O2S319.7635 / 04.2Yes
4431032D structureCHEMBL3334932C21H19N3O2345.4024 / 12.9Yes
5226022D structureCHEMBL3718689C27H22N4O5S2546.6169 / 04.2No
5226062D structureCHEMBL3730607C26H21N5O5S515.54410 / 04.4No
5226262D structureCHEMBL3728380C20H15ClN4O2S410.8766 / 05.3No
5226302D structureCHEMBL3715042C26H28N6O4S520.60810 / 12.9No
5226312D structureCHEMBL3728211C13H7F3N4OS3388.40110 / 05.0Yes
5226422D structureCHEMBL3718490C29H31N5O6S2609.71611 / 13.9No
5226642D structureCHEMBL3729657C13H9FN4OS288.36 / 03.3Yes
5226672D structureCHEMBL3715479C25H18FN5O3S487.5099 / 04.4Yes
5227172D structureCHEMBL3719033C22H19N5O4S449.4859 / 03.6Yes
5227292D structureCHEMBL3731815C21H17N3O4S407.4447 / 14.8Yes
5227612D structureCHEMBL3733243C18H13N5O2S2395.4558 / 03.6Yes
5227642D structureCHEMBL3718187C28H24N4O5S528.5839 / 05.9No
5227742D structureCHEMBL3731269C15H13N3O2S299.3485 / 04.0Yes
5227882D structureCHEMBL3717023C24H21F3N4O4S2550.57112 / 05.7No
5227902D structureCHEMBL3716344C27H23N5O6S545.5711 / 04.5No
5228052D structureCHEMBL3715746C29H25N3O5S527.5958 / 06.7No
5228102D structureCHEMBL3731161C13H8FN3O2S289.2846 / 03.4Yes
5228212D structureCHEMBL3719385C25H25N5O4S491.5669 / 14.1Yes
5228242D structureCHEMBL3733049C14H8ClF2N3OS339.7456 / 04.4Yes
5228332D structureCHEMBL3717959C26H19FN4O4S502.529 / 05.7No
5228782D structureCHEMBL3718712C23H24N4O5S2500.58810 / 14.6No
5228922D structureCHEMBL3718220C24H18N6O4S2518.56611 / 04.7No
5229032D structureCHEMBL3716059C24H24N4O6S2528.59811 / 13.5No
5229842D structureCHEMBL3732521C18H13N5O2S2395.4558 / 03.7Yes
5229862D structureCHEMBL3716687C28H22N6O3S522.5838 / 25.3No
5230162D structureCHEMBL3719287C25H18ClN5O4S519.969 / 05.1No
5230192D structureCHEMBL3729522C22H25N3O4S427.5197 / 05.0Yes
5230212D structureCHEMBL3718116C22H22N4O6S2502.5611 / 03.3No
5230362D structureCHEMBL3728622C14H7Cl2F2N3OS374.1876 / 05.0Yes
5230492D structureCHEMBL3719245C28H23FN4O5S2578.63311 / 05.6No
5230642D structureCHEMBL3731802C14H10BrN3O3S380.2166 / 03.9Yes
5230682D structureCHEMBL3716623C23H22N4O6S2514.57111 / 13.1No
5230692D structureCHEMBL3728392C20H16N4O4S408.4328 / 04.1Yes
5230732D structureCHEMBL3715215C27H23N5O5S2561.63110 / 15.1No
5230892D structureCHEMBL3719223C32H31N5O6S2645.74911 / 05.3No
5230902D structureCHEMBL3714802C23H24ClN5O5S2550.04511 / 2N/ANo

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