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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameP2Y purinoceptor 12
SpeciesRattus norvegicus (Rat)
GeneP2ry12
SynonymP2YADP
HORK3
purinergic receptor P2Y
SP1999
P2Y12 platelet ADP receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length343
Amino acid sequenceMEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM
UniProtQ9EPX4
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2188
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 116
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
4418292D structureCHEMBL3325646C31H36N6O3540.6685 / 23.5No
30572D structureCHEMBL3098242C23H27F3N6O4S540.56213 / 42.1No
4423892D structureCHEMBL3325636C33H40N6O3568.7225 / 14.2No
4424372D structureCHEMBL3325626C27H28N4O4472.5455 / 24.1Yes
4425512D structureCHEMBL3325804C34H36ClN7O4642.1577 / 14.2No
4426492D structureCHEMBL3325891C28H31ClN8O3563.0597 / 12.4No
4427772D structureCHEMBL3325783C32H36F2N6O3590.6767 / 14.4No
4427822D structureCHEMBL3325639C32H38N6O3554.6955 / 24.1No
4429172D structureCHEMBL3325633C30H36N6O3528.6575 / 23.3No
4430552D structureCHEMBL3325661C34H40N6O3580.7335 / 14.3No
4430702D structureCHEMBL3325793C31H35ClN6O3575.115 / 14.1No
375982D structurealpha,beta-Methylene ATPC11H18N5O12P3505.20916 / 7-5.9No
4432072D structureCHEMBL3325652C36H44N6O3608.7875 / 15.1No
388152D structureCHEMBL129841C11H17N5O9P2425.23113 / 5-2.9No
4434812D structureCHEMBL3326904C28H30N4O4486.5725 / 24.6Yes
4435592D structureCHEMBL3325892C28H31ClN8O3563.0597 / 12.3No
4436362D structureCHEMBL3325649C32H38N6O3554.6955 / 23.8No
4436822D structureCHEMBL3325663C33H38N6O3566.7065 / 14.1No
508822D structureCHEMBL3098234C21H27ClN6O4S2527.05511 / 42.5No
4438452D structureCHEMBL3325894C29H38ClN7O3568.1196 / 13.0No
4441702D structureCHEMBL3325785C34H40N6O4596.7326 / 23.5No
4443372D structureCHEMBL3325795C31H35BrN6O3619.5645 / 14.2No
4445722D structureCHEMBL3325631C31H37ClN6O3577.1265 / 2N/ANo
4446282D structureCHEMBL3325648C31H36N6O3540.6685 / 23.3No
4447062D structureCHEMBL3325800C31H35N7O4569.6666 / 22.0No
788722D structuresuraminC51H40N6O23S61297.2623 / 121.5No
4448642D structureCHEMBL3325780C33H40N6O3568.7225 / 14.4No
4452172D structureCHEMBL3326908C27H28N4O4472.5455 / 14.0Yes
4452222D structureCHEMBL3325634C30H36N6O3528.6575 / 23.6No
4454642D structureCHEMBL3325644C31H36N6O3540.6685 / 23.3No
4456962D structureCHEMBL3325660C33H40N6O4584.7216 / 13.4No
4457412D structureCHEMBL3325664C33H40N6O3568.7225 / 14.3No
1113312D structureAdpbetasC10H15N5O9P2S443.26414 / 6-2.9No
1152252D structureCHEMBL3098250C24H29F3N6O4S554.58913 / 42.4No
4467442D structureCHEMBL3325656C33H38N6O3566.7065 / 13.8No
4470162D structureCHEMBL3326907C26H26N4O4458.5185 / 23.8Yes
1541322D structureCHEMBL3098241C21H23F3N6O3S496.50912 / 42.2No
1545302D structureCHEMBL3098246C21H22F2N6O2S460.50410 / 33.0Yes
1577752D structureBasilen BlueC29H17ClN7O11S3-3771.12318 / 44.1No
1578362D structureCHEMBL3098240C21H24F2N6O4S494.51812 / 51.2No
4479582D structureCHEMBL3325632C30H34N6O3526.6415 / 33.3No
4484142D structureCHEMBL3325659C32H38N6O4570.6946 / 22.8No
4484552D structureCHEMBL3325784C32H35F3N6O3608.6668 / 14.6No
1806722D structureCHEMBL3098236C22H29N7O4S487.57911 / 40.8No
4488732D structureCHEMBL3326905C28H30N4O4486.5725 / 23.9Yes
4488992D structureCHEMBL3325782C32H37FN6O3572.6856 / 13.9No
4489972D structureCHEMBL3325665C31H36N6O3540.6685 / 23.5No
4493302D structureCHEMBL3325635C32H38N6O3554.6955 / 24.1No
4494102D structureCHEMBL3325803C33H38ClN7O4632.1626 / 13.3No
4495832D structureCHEMBL3325643C32H38N6O3554.6955 / 13.9No
4496652D structureCHEMBL3325637C31H33N7O3551.6515 / 23.2No
4497352D structureCHEMBL3325895C30H32ClN5O4562.0676 / 04.4No
4497732D structureCHEMBL3325797C30H32Cl2N6O3595.5255 / 14.4No
2062942D structureCHEMBL3098235C21H29N7O4S2507.62812 / 41.3No
4500212D structureCHEMBL3325650C33H40N6O3568.7225 / 14.3No
2204312D structureCHEMBL3085531C13H18ClN5O8P2469.71212 / 5-1.6No
4504552D structureCHEMBL3325898C31H34ClN7O4604.1086 / 23.2No
2265282D structuregamma-Thio-ATPC10H16N5O12P3S523.24217 / 7-4.0No
4507532D structureCHEMBL3325645C32H38N6O3554.6955 / 23.8No
4508702D structureCHEMBL3325658C34H42N6O3582.7495 / 14.8No
2392272D structureTicagrelorC23H28F2N6O4S522.57212 / 42.0No
4511092D structureCHEMBL3325788C37H39FN6O3634.7566 / 15.1No
4513482D structureCHEMBL3325630C32H39ClN6O3591.1535 / 2N/ANo
4513592D structureCHEMBL3325794C31H33N7O3551.6516 / 12.9No
4514442D structureCHEMBL3325651C32H38N6O3554.6955 / 23.7No
4514992D structureCHEMBL3325806C29H31ClN6O3547.0565 / 13.4No
4515392D structureCHEMBL3098237C23H30N6O4S486.59110 / 41.9Yes
4516112D structureCHEMBL3325896C31H32ClN7O3586.0936 / 14.1No
4516172D structureCHEMBL3325789C31H36N6O4556.6676 / 13.1No
4516422D structureCHEMBL3325801C32H37ClN6O4605.1366 / 13.6No
2570002D structureCHEMBL3098249C24H30F2N6O5S552.59813 / 51.4No
4519122D structureCHEMBL3325666C32H38N6O3554.6955 / 14.0No
5654762D structureppadsC14H14N3O12PS2511.36915 / 5-1.5No
4523452D structureCHEMBL3325779C32H38N6O3554.6955 / 23.9No
4524282D structureCHEMBL3098248C25H32F2N6O5S566.62513 / 41.9No
2723732D structureCHEMBL3098247C21H23F3N6O2S480.5111 / 33.2No
4524972D structureCHEMBL3325787C32H36N6O3552.6795 / 13.8No
4526402D structureCHEMBL3325805C33H36ClN7O4630.1466 / 13.1No
4527112D structureCHEMBL3325657C32H38N6O3554.6955 / 13.9No
4537612D structureCHEMBL3325790C30H32ClFN6O3579.0736 / 13.9No
4539472D structureCHEMBL3325647C32H38N6O3554.6955 / 13.9No
4539502D structureCHEMBL3325640C32H38N6O3554.6955 / 13.9No
4540132D structureCHEMBL3326906C27H28N4O4472.5455 / 23.5Yes
4541662D structureCHEMBL3325791C31H35BrN6O3619.5645 / 14.2No
4550242D structureCHEMBL3325807C28H29ClN6O3533.0295 / 13.0No
4550302D structureCHEMBL3325802C31H35ClN6O4591.1096 / 23.1No
3360222D structureAMP-PCPC11H18N5O12P3505.20916 / 7-5.9No
4550712D structureCHEMBL3326903C26H30N4O5478.5496 / 33.6Yes
4552092D structureCHEMBL3325638C31H38N6O3542.6845 / 24.0No
4554702D structureCHEMBL3325625C27H28N4O4472.5455 / 24.2Yes
4557602D structureCHEMBL3325655C32H36N6O3552.6795 / 23.3No
4557652D structureCHEMBL3325796C31H35ClN6O3575.115 / 14.1No
4558102D structureCHEMBL3325641C32H38N6O3554.6955 / 24.1No
4558242D structureCHEMBL3325792C31H33F3N6O3594.6398 / 14.0No
4559852D structureCHEMBL3325808C30H30ClF3N6O3615.0548 / 14.4No
3633352D structureCHEMBL3098239C23H28F2N6O5S538.57113 / 51.1No
4561302D structureCHEMBL3325629C29H33N5O3499.6154 / 14.1Yes
3681212D structureCID 136908877C29H17ClN7Na3O11S3840.09215 / 4N/ANo
4564532D structureCHEMBL3325662C33H38N6O3566.7065 / 14.1No
4564902D structureCHEMBL3325653C32H36N6O3552.6795 / 23.5No

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