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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

Name5-hydroxytryptamine receptor 6
SpeciesMus musculus (Mouse)
GeneHtr6
Synonym5-HT-6
5-HT6
5-HT6 receptor
5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
Serotonin receptor 6
[ Show all ]
DiseaseN/A for non-human GPCRs
Length440
Amino acid sequenceMVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTSAPGQCRLLASLPYVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTATAGQALETLQVPRTPRPGMESADSRRLTTKHSRKALKASLTLGILLSMFFVTWLPFFVASIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFVPCVHCPPEHRASPASPSMWTSHSGARPGLSLQQVLPLPLPPNSDSDSASGGTSGLQLTAQLLLPGEATRDPPPPTRAPTVVNFFVTDSVEPEIRQHPLGSPMN
UniProtQ9R1C8
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1075268
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 42
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
117452D structurepropranololC16H21NO2259.3493 / 23.0Yes
136842D structure8-OH-DpatC16H25NO247.3822 / 14.1Yes
209362D structureSB-258585C18H22IN3O3S487.3566 / 13.0Yes
231682D structure1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amineC11H16INO2321.1583 / 12.5Yes
270522D structureSB-357134C17H18Br2FN3O3S523.2157 / 23.4No
566892D structurecisaprideC23H29ClFN3O4465.957 / 23.4Yes
622432D structurespiperoneC23H26FN3O2395.4785 / 13.0Yes
838802D structureKetanserinC22H22FN3O3395.4345 / 12.6Yes
1015262D structureUNII-UGT5535REQC17H18ClNO287.7872 / 14.0Yes
1056532D structureRemoxiprideC16H23BrN2O3371.2754 / 12.1Yes
1489632D structureRo 04-6790C12H16N6O2S308.368 / 41.7Yes
1540362D structureMesulergineC18H26N4O2S362.4925 / 11.4Yes
1593422D structure5-METHOXYTRYPTAMINEC11H14N2O190.2462 / 20.5Yes
1639562D structurepindololC14H20N2O2248.3263 / 31.8Yes
1711612D structure15532-75-9C11H13F3N2230.2345 / 12.3Yes
1748942D structuremethysergideC21H27N3O2353.4663 / 22.3Yes
1756592D structuresumatriptanC14H21N3O2S295.4014 / 20.9Yes
1764642D structureamitriptylineC20H23N277.4111 / 05.0Yes
1767012D structureRU 24969C14H16N2O228.2952 / 21.8Yes
1916072D structurehaloperidolC21H23ClFNO2375.8684 / 13.2Yes
1922142D structureSB-271046C20H22ClN3O3S2451.9847 / 24.2Yes
2543382D structurebromocriptineC32H40BrN5O5654.6066 / 33.8No
2544722D structureSB-214111C18H22BrN3O3S440.3566 / 13.0Yes
2559452D structureDihydroergocryptineC32H43N5O5577.7266 / 33.1No
2883252D structurebuspironeC21H31N5O2385.5126 / 02.6Yes
2902752D structureserotoninC10H12N2O176.2192 / 30.2Yes
2988462D structure1H-Indol-5-ol, 3-(2-aminoethyl)-1-methyl-C11H14N2O190.2462 / 21.0Yes
2990212D structuremethiothepinC20H24N2S2356.5464 / 04.2Yes
3071342D structureCHEMBL584690C23H22N4O370.4564 / 14.3Yes
3129992D structuredl-ArterenolC8H11NO3169.184 / 4-1.2Yes
3350022D structure(S)-mianserinC18H20N2264.3722 / 03.4Yes
3505512D structureD-Lysergic acid N,N-diethylamideC20H25N3O323.442 / 13.0Yes
3574162D structure2-Bromolysergic acid diethylamideC20H24BrN3O402.3362 / 14.0Yes
3641112D structureBufotenineC12H16N2O204.2732 / 21.2Yes
3671642D structuredopamineC8H11NO2153.1813 / 3-1.0Yes
3858012D structure2-Methyl-5-hydroxytryptamineC11H14N2O190.2462 / 31.4Yes
3861572D structuremetergolineC25H29N3O2403.5263 / 13.8Yes
3882812D structureERGOTAMINEC33H35N5O5581.6736 / 32.0No
4147252D structureCHEBI:31843C18H21ClN2300.833 / 1N/AN/A
4293802D structureSB-258510C21H24ClN3O3S2466.0117 / 14.7Yes
4340722D structurechlorpromazineC17H19ClN2S318.8633 / 05.2No
4412162D structure(+)-ButaclamolC25H31NO361.5292 / 15.0Yes

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