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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameGamma-aminobutyric acid type B receptor subunit 1
SpeciesHomo sapiens (Human)
GeneGABBR1
SynonymGABABR1
GABA-BR1
GABAB1
GABA-B-R1
gamma-aminobutyric acid (GABA) B receptor 1
[ Show all ]
DiseaseN/A
Length961
Amino acid sequenceMLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK
UniProtQ9UBS5
Protein Data Bank4mr9, 4mrm, 4ms3, 4ms4, 4mqe, 4mqf, 4ms1
GPCR-HGmod modelN/A
3D structure modelThis structure is from PDB ID 4mr9.
BioLiPBL0264371, BL0264367, BL0264366, BL0264365, BL0264356, BL0264357, BL0264358, BL0264359, BL0264368, BL0264369, BL0264370
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2064
IUPHAR240
DrugBankBE0000217

Known ligands

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Total entries: 29
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
171462D structureCHEMBL2440659C15H11FN4O2S330.3377 / 12.4Yes
322332D structure4-aminobutyric acidC4H9NO2103.1213 / 2-3.2Yes
469702D structureCHEMBL445449C6H12NO2P161.1413 / 2-3.5Yes
469712D structureCHEMBL504482C6H12NO2P161.1413 / 2-3.5Yes
469722D structureCHEMBL447171C6H12NO2P161.1413 / 2-3.5Yes
623902D structureCHEMBL453966C7H14NO2P175.1683 / 2-3.2Yes
966062D structureCHEMBL507116C8H16NO2P189.1953 / 2-2.7Yes
1238742D structureCHEMBL1939222C10H8Cl2N2O2259.0863 / 22.5Yes
5560072D structureAbt-418C9H14N2O166.2243 / 01.2Yes
1575812D structureML315C18H13Cl2N3O2374.2215 / 14.7Yes
5499392D structureArbaclofen placarbilC19H26ClNO6399.8686 / 24.2Yes
5500922D structure(R)-BaclofenC10H12ClNO2213.6613 / 2-1.0Yes
1752582D structurebaclofenC10H12ClNO2213.6613 / 2-1.0Yes
5269912D structureCHEMBL3763166C14H12BrN3O3S382.2325 / 32.3Yes
5502672D structureUNII-6XN50U405YC13H23N5O3297.3597 / 4N/AN/A
2043932D structureTPMPAC6H12NO2P161.1413 / 2-3.5Yes
5509192D structureCgp-36742C7H18NO2P179.23 / 2-2.7Yes
2610502D structureCID 25202592C6H11NO2129.1592 / 1-1.5Yes
4520712D structureCHEMBL3310802C27H39N5O7545.6379 / 2N/ANo
5567882D structureSCHEMBL1432281C29H34ClN3O476.0612 / 17.4No
5549102D structureCGP-47656C4H10F2NO2P173.15 / 2-3.0Yes
5520862D structuregabapentinC9H17NO2171.243 / 2-1.1Yes
3702472D structureCHEMBL486434C9H18NO2P203.2223 / 2-2.3Yes
3702482D structureSCHEMBL3894140C9H18NO2P203.2223 / 2-2.3Yes
3702492D structureCHEMBL507241C9H18NO2P203.2223 / 2-2.3Yes
3781442D structureCHEMBL487279C12H16NO2P237.2393 / 2-2.0Yes
5571232D structureA-85380C9H12N2O164.2083 / 10.6Yes
5527712D structuretaurineC2H7NO3S125.1424 / 2-4.1Yes
4348132D structureCGP 54626 HYDROCHLORIDEC18H29Cl3NO3P444.7584 / 4N/AN/A

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