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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameProstaglandin D2 receptor 2
SpeciesMus musculus (Mouse)
GenePtgdr2
SynonymPGD2 receptor
Gpr44
G-protein coupled receptor 44
G protein-coupled receptor 44
DP2 receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length382
Amino acid sequenceMANVTLKPLCPLLEEMVQLPNHSNSSLRYIDHVSVLLHGLASLLGLVENGLILFVVGCRMRQTVVTTWVLHLALSDLLAAASLPFFTYFLAVGHSWELGTTFCKLHSSVFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAVAHRVCLMLWALAVLNTIPYFVFRDTIPRLDGRIMCYYNLLLWNPGPDRDTTCDYRQKALAVSKFLLAFMVPLAIIASSHVAVSLRLHHRGRQRTGRFVRLVAAIVVAFVLCWGPYHIFSLLEARAHSVTTLRQLASRGLPFVTSLAFFNSVVNPLLYVFTCPDMLYKLRRSLRAVLESVLVEDSDQSGGLRNRRRRASSTATPASTLLLADRIPQLRPTRLIGWMRRGSAEVPQRV
UniProtQ9Z2J6
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2291
IUPHAR339
DrugBankN/A

Known ligands

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Total entries: 28
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
12102D structureCHEMBL409714C20H15Cl2FN2O4437.2485 / 12.5Yes
12112D structureCHEMBL260013C20H15Cl2FN2O4437.2485 / 12.5Yes
15242D structureCHEMBL1088284C25H17F3N2O2434.4187 / 15.0Yes
5532972D structurePGD3C20H30O5350.4555 / 32.0Yes
213132D structureSpiro-indolinone analogue, 89C20H17ClN2O4384.8164 / 11.7Yes
5533752D structureprostaglandin D2C20H32O5352.4715 / 32.6Yes
5534482D structureindomethacinC19H16ClNO4357.794 / 14.3Yes
636292D structureCHEMBL217053C18H13BrN2O4401.2165 / 13.5Yes
816282D structureCHEMBL1917592C19H16ClFO5S410.846 / 14.4Yes
1182002D structureCHEMBL563949C16H12F2N2O4S366.3397 / 12.6Yes
1349312D structureCHEMBL3236948C23H21FN2O3392.434 / 13.8Yes
1440692D structureCHEMBL260672C20H13Cl2FN2O5451.2316 / 12.4Yes
1665632D structureCHEMBL1778639C18H17F3O5S402.3848 / 14.0Yes
5541982D structureRamatrobanC21H21FN2O4S416.4676 / 22.9Yes
1946922D structureCHEMBL1917389C16H10Cl2O3321.1533 / 14.8Yes
2683192D structureCHEMBL411315C20H14Cl2N2O5433.2415 / 12.3Yes
5546292D structuredinoprostC20H34O5354.4875 / 42.7Yes
2771802D structureCHEMBL1917584C20H19ClO5S406.8775 / 14.6Yes
5546972D structure15-deoxy-PGD2C20H30O4334.4564 / 23.8Yes
3165702D structureCHEMBL260674C20H14ClFN2O5416.7896 / 11.8Yes
5548972D structuredelta(12)-PGJ2C20H30O4334.4564 / 23.9Yes
5549852D structureprostaglandin J2C20H30O4334.4564 / 23.6Yes
5550612D structure15deoxy-delta-12,14-PGJ2C20H28O3316.4413 / 15.0Yes
5550842D structure13,14-Dihydro-15-keto-pgd2C20H32O5352.4715 / 22.4Yes
5552472D structureProstaglandin E2C20H32O5352.4715 / 32.8Yes
4155052D structureNVP-QAV680C18H18N2O4S358.4125 / 12.0Yes
4248682D structureSpiro-indolinone analogue, 5C20H15ClN2O5398.7995 / 11.7Yes
4371352D structureCHEMBL2204469C23H18F3N3O3441.417 / 13.3Yes

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