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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000027156
Molecular formula	C23H30N6
IUPAC name	4-[(1-tert-butyltetrazol-5-yl)-(3,4-dihydro-1H-isoquinolin-2-yl)methyl]-N,N-dimethylaniline
Molecular weight	390.535
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.7
Synonyms	HMS2311F14 Oprea1_660480 AC1LCNXS SR-01000337278-1 SMR000004466 AKOS000687911 CHEMBL1426925 {4-[(1-tert-Butyl-1H-tetrazol-5-yl)-(3,4-dihydro-1H-isoquinolin-2-yl)-methyl]-phenyl}-dimethyl-amine Oprea1_607477 4-[(1-tert-butyltetrazol-5-yl)-(3,4-dihydro-1H-isoquinolin-2-yl)methyl]-N,N-dimethylaniline ASN 05346330 SR-01000337278 [ Show all ]
Inchi Key	AAFZDYDDZPHGMB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H30N6/c1-23(2,3)29-22(24-25-26-29)21(18-10-12-20(13-11-18)27(4)5)28-15-14-17-8-6-7-9-19(17)16-28/h6-13,21H,14-16H2,1-5H3
PubChem CID	653221
ChEMBL	CHEMBL1426925
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
182	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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