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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2420770
Molecular formula	C15H17FN2S
IUPAC name	1-(2-fluorophenyl)-4-(thiophen-2-ylmethyl)piperazine
Molecular weight	276.373
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.2
Synonyms	1-(2-fluorophenyl)-4-(thiophen-2-ylmethyl)piperazine MolPort-002-140-672 AC1LG0I7 Oprea1_197772 BDBM50439444 MCULE-6452805205 AB00077247-01 Oprea1_620284 [ Show all ]
Inchi Key	ABPMRHGOCCQDFC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H17FN2S/c16-14-5-1-2-6-15(14)18-9-7-17(8-10-18)12-13-4-3-11-19-13/h1-6,11H,7-10,12H2
PubChem CID	763194
ChEMBL	CHEMBL2420770
IUPHAR	N/A
BindingDB	50439444
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1063	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
1060	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
1062	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
1061	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
1059	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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