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Ligand

NameSB-0304
Molecular formulaC25H29N5O5
IUPAC name(2R)-2-[(4S)-4-amino-8-hydroxy-3-oxo-4,5-dihydro-1H-2-benzazepin-2-yl]-N-[(4S)-2-(2-amino-2-oxoethyl)-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]propanamide
Molecular weight479.537
Hydrogen bond acceptor6
Hydrogen bond donor4
XlogP-0.2
SynonymsBDBM50376593
CHEMBL409225
D08LIT
Inchi KeyACFTTXWQZSBVGL-OREJSRFESA-N
Inchi IDInChI=1S/C25H29N5O5/c1-14(30-12-18-8-19(31)7-6-16(18)9-20(26)24(30)34)23(33)28-21-10-15-4-2-3-5-17(15)11-29(25(21)35)13-22(27)32/h2-8,14,20-21,31H,9-13,26H2,1H3,(H2,27,32)(H,28,33)/t14-,20+,21+/m1/s1
PubChem CID11641503
ChEMBLCHEMBL409225
IUPHARN/A
BindingDB50376593
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 7
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1529Delta-type opioid receptorP33533Oprd1Rattus norvegicus (Rat)372
1531Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
1534Delta-type opioid receptorP32300Oprd1Mus musculus (Mouse)372
1533Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
1528Mu-type opioid receptorP97266OPRM1Cavia porcellus (Guinea pig)98
1530Mu-type opioid receptorP33535Oprm1Rattus norvegicus (Rat)398
1532Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400

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