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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL210461
Molecular formula	C31H35Cl2N3O
IUPAC name	N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
Molecular weight	536.541
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	7.3
Synonyms	N-[4-(4-(2,3-dichlorophenyl)piperazin-1-yl]butyl][2.2]-paracyclophane-4-carboxamide BDBM50188478
Inchi Key	ACKGCCXJFAZCFF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H35Cl2N3O/c32-28-4-3-5-29(30(28)33)36-20-18-35(19-21-36)17-2-1-16-34-31(37)27-22-25-11-10-23-6-8-24(9-7-23)12-14-26(27)15-13-25/h3-9,13,15,22H,1-2,10-12,14,16-21H2,(H,34,37)
PubChem CID	11706497
ChEMBL	CHEMBL210461
IUPHAR	N/A
BindingDB	50188478
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1658	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
1654	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
1656	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
1657	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
1655	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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