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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000537663
Molecular formula	C24H21NO2
IUPAC name	10-[bis(4-methylphenyl)methylidene]-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
Molecular weight	355.437
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.1
Synonyms	cid_2957057 STL384155 AKOS000366737 SR-01000278505 8-[bis(4-methylphenyl)methylidene]-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione HMS2396K19 AKOS025250056 MolPort-002-094-101 10-[bis(4-methylphenyl)methylene]-4-azatricyclo[5.2.1.0~2,6~]dec-8-ene-3,5-dione CHEMBL1446969 SR-01000278505-1 AC1MG89F MCULE-4140876807 BDBM79974 SMR000143904 [ Show all ]
Inchi Key	ACTMDNIAXPEGIL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H21NO2/c1-13-3-7-15(8-4-13)19(16-9-5-14(2)6-10-16)20-17-11-12-18(20)22-21(17)23(26)25-24(22)27/h3-12,17-18,21-22H,1-2H3,(H,25,26,27)
PubChem CID	2957057
ChEMBL	CHEMBL1446969
IUPHAR	N/A
BindingDB	79974
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1894	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
1893	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
1892	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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