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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000628313
Molecular formula	C24H29N3O4S
IUPAC name	cyclopropyl-[5-[4-(3-methoxyphenyl)piperazin-1-yl]sulfonyl-2-methyl-2,3-dihydroindol-1-yl]methanone
Molecular weight	455.573
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.9
Synonyms	HMS2925N12 MLS001122769 HMS3473C09 1-(cyclopropylcarbonyl)-5-{[4-(3-methoxyphenyl)piperazin-1-yl]sulfonyl}-2-methylindoline MLS003880910 CHEMBL1585939 MCULE-8841779492 AKOS001932826 [ Show all ]
Inchi Key	ADKGEMATJYFJHH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29N3O4S/c1-17-14-19-15-22(8-9-23(19)27(17)24(28)18-6-7-18)32(29,30)26-12-10-25(11-13-26)20-4-3-5-21(16-20)31-2/h3-5,8-9,15-18H,6-7,10-14H2,1-2H3
PubChem CID	20901625
ChEMBL	CHEMBL1585939
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2377	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463216	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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