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Ligand

NameCHEMBL446459
Molecular formulaC14H19F2N3O
IUPAC nameN-(2,2-difluoroethyl)-4-methyl-8-propan-2-yloxy-3,4-dihydro-1H-quinazolin-2-imine
Molecular weight283.323
Hydrogen bond acceptor4
Hydrogen bond donor2
XlogP2.6
SynonymsBDBM50371980
SCHEMBL1379614
Inchi KeyADOGGHZNEGBRNB-UHFFFAOYSA-N
Inchi IDInChI=1S/C14H19F2N3O/c1-8(2)20-11-6-4-5-10-9(3)18-14(19-13(10)11)17-7-12(15)16/h4-6,8-9,12H,7H2,1-3H3,(H2,17,18,19)
PubChem CID135458427
ChEMBLCHEMBL446459
IUPHARN/A
BindingDB50371980
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
29155-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
29145-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
29175-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
29165-hydroxytryptamine receptor 5AP47898HTR5AHomo sapiens (Human)357
29185-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479

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