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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N-[2-(4-chlorophenyl)ethyl]-N'-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]succinamide
Molecular formula	C27H32ClN5O2
IUPAC name	N-[2-(4-chlorophenyl)ethyl]-N'-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]butanediamide
Molecular weight	494.036
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.8
Synonyms	AKOS001826904 SMR000559496 HMS2855B13 MolPort-007-602-364 ZINC20136318 MCULE-3973906852 CHEMBL1882722 MLS001198134 [ Show all ]
Inchi Key	ADVSKIXXIGPFPI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H32ClN5O2/c1-19-17-25(33-15-13-32(2)14-16-33)31-24-8-7-22(18-23(19)24)30-27(35)10-9-26(34)29-12-11-20-3-5-21(28)6-4-20/h3-8,17-18H,9-16H2,1-2H3,(H,29,34)(H,30,35)
PubChem CID	22427035
ChEMBL	CHEMBL1882722
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463264	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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