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Ligand

Nametetrahydropalmatine
Molecular formulaC21H25NO4
IUPAC name(13aS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
Molecular weight355.434
Hydrogen bond acceptor5
Hydrogen bond donor0
XlogP3.2
Synonymsl-Tetrahydropalmatine
Rotundine
483-14-7
(-)-Tetrahydropalmatine
(S)-Tetrahydropalmatine
[ Show all ]
Inchi KeyAEQDJSLRWYMAQI-KRWDZBQOSA-N
Inchi IDInChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m0/s1
PubChem CID72301
ChEMBLCHEMBL487182
IUPHARN/A
BindingDB50424077
DrugBankDB12093

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
37435-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
37405-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
536014Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
3741D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
3742D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443

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