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Ligand

NameCHEMBL3965933
Molecular formulaC19H20F3N5O
IUPAC name3-cyclopropyl-N-[(1S,2S)-2-[[5-(trifluoromethyl)pyrazin-2-yl]amino]cyclopentyl]pyridine-2-carboxamide
Molecular weight391.398
Hydrogen bond acceptor8
Hydrogen bond donor2
XlogP3.1
Synonyms3-Cyclopropyl-N-[(1S,2S)-2-{[5-(trifluoromethyl)pyrazin-2-yl]amino}cyclopentyl]pyridine-2-carboxamide
AFBKMNNXFDRXES-KBPBESRZSA-N
BDBM185247
SCHEMBL17007240
US9156829, 63
Inchi KeyAFBKMNNXFDRXES-KBPBESRZSA-N
Inchi IDInChI=1S/C19H20F3N5O/c20-19(21,22)15-9-25-16(10-24-15)26-13-4-1-5-14(13)27-18(28)17-12(11-6-7-11)3-2-8-23-17/h2-3,8-11,13-14H,1,4-7H2,(H,25,26)(H,27,28)/t13-,14-/m0/s1
PubChem CID118308193
ChEMBLCHEMBL3965933
IUPHARN/A
BindingDB185247
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
536024Orexin receptor type 1O43613HCRTR1Homo sapiens (Human)425
536025Orexin receptor type 2O43614HCRTR2Homo sapiens (Human)444

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