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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000131154
Molecular formula	C18H23N3O4S
IUPAC name	N-(3-methoxypropyl)-4-oxo-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1H-quinazoline-7-carboxamide
Molecular weight	377.459
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	1.1
Synonyms	AC1N5BW7 MolPort-007-910-164 MCULE-4001186677 AKOS002085907 N-(3-methoxypropyl)-4-oxo-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1H-quinazoline-7-carboxamide CHEMBL1505600 SR-01000557486 MLS000520744 AKOS021646700 N-(3-methoxypropyl)-4-oxo-3-(tetrahydrofuran-2-ylmethyl)-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide HMS2412F24 SR-01000557486-1 [ Show all ]
Inchi Key	AFGCTQNGZJQBNM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H23N3O4S/c1-24-8-3-7-19-16(22)12-5-6-14-15(10-12)20-18(26)21(17(14)23)11-13-4-2-9-25-13/h5-6,10,13H,2-4,7-9,11H2,1H3,(H,19,22)(H,20,26)
PubChem CID	4142546
ChEMBL	CHEMBL1505600
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463387	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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