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Ligand

NameCHEMBL1783868
Molecular formulaC20H18N4OS
IUPAC name5-(4-methylphenyl)-13-(2-methylprop-2-enylamino)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight362.451
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP4.7
SynonymsSCHEMBL8244563
BDBM50345941
9-(2-Methyl-allylamino)-3-p-tolyl-3H-pyrido[3'',2'':4,5]thieno[3,2-d]pyrimidin-4-one
Inchi KeyAFKSTFXIAKZKBK-UHFFFAOYSA-N
Inchi IDInChI=1S/C20H18N4OS/c1-12(2)10-22-15-8-9-21-19-16(15)17-18(26-19)20(25)24(11-23-17)14-6-4-13(3)5-7-14/h4-9,11H,1,10H2,2-3H3,(H,21,22)
PubChem CID54585405
ChEMBLCHEMBL1783868
IUPHARN/A
BindingDB50345941
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
4246Metabotropic glutamate receptor 1P23385Grm1Rattus norvegicus (Rat)1199
4247Metabotropic glutamate receptor 1Q13255GRM1Homo sapiens (Human)1194
4245Metabotropic glutamate receptor 5P41594GRM5Homo sapiens (Human)1212

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