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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-(2-ethylphenyl)-4-[(4-fluoro-3-methylphenyl)sulfonyl]piperazine
Molecular formula	C19H23FN2O2S
IUPAC name	1-(2-ethylphenyl)-4-(4-fluoro-3-methylphenyl)sulfonylpiperazine
Molecular weight	362.463
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.9
Synonyms	HMS2367E21 AC1M33TI MolPort-000-519-594 1-(2-ethylphenyl)-4-(4-fluoro-3-methylbenzenesulfonyl)piperazine Z1171201074 4-{[4-(2-ethylphenyl)piperazinyl]sulfonyl}-1-fluoro-2-methylbenzene MCULE-7150512664 AKOS002273761 SMR000076546 1-(2-ethylphenyl)-4-(4-fluoro-3-methylphenyl)sulfonylpiperazine CHEMBL1506415 ZINC2852407 701927-35-7 MLS000064342 AP-263/42373719 ST50171313 [ Show all ]
Inchi Key	AFOUVFGRVMRYEN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H23FN2O2S/c1-3-16-6-4-5-7-19(16)21-10-12-22(13-11-21)25(23,24)17-8-9-18(20)15(2)14-17/h4-9,14H,3,10-13H2,1-2H3
PubChem CID	2206049
ChEMBL	CHEMBL1506415
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4367	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
4368	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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