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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1NO6UM
Molecular formula	C20H25ClN6OS
IUPAC name	2-[[5-(2-chlorophenyl)-4-imino-3-methyl-2H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl]-N,N-diethylbutanamide
Molecular weight	432.971
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.3
Synonyms	2-[4-amino-5-(2-chlorophenyl)-3-methylpyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl-N,N-diethylbutanamide K898-1522 AKOS002118523 NCGC00140758-01 CHEMBL1396837 SR-01000592091-1 2-{[5-(2-chlorophenyl)-4-imino-3-methyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl]thio}-N,N-diethylbutanamide MCULE-6640444129 AKOS021672619 Oprea1_072490 HMS1916P05 MolPort-007-949-239 SR-01000592091 [ Show all ]
Inchi Key	AFXJCUFNEDDTMR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H25ClN6OS/c1-5-15(19(28)26(6-2)7-3)29-20-23-18-16(12(4)24-25-18)17(22)27(20)14-11-9-8-10-13(14)21/h8-11,15,22H,5-7H2,1-4H3,(H,24,25)
PubChem CID	135407490
ChEMBL	CHEMBL1396837
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557410	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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