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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	6060-00-0
Molecular formula	C26H19N5O3
IUPAC name	2-[2-[3-(1-methylbenzimidazol-2-yl)-4-oxoquinazolin-2-yl]ethyl]isoindole-1,3-dione
Molecular weight	449.47
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.9
Synonyms	2-[2-[3-(1-methylbenzimidazol-2-yl)-4-oxoquinazolin-2-yl]ethyl]isoindole-1,3-dione BRD-K85265551-001-02-1 MolPort-001-966-594 SMR000105679 BAS 01817183 MCULE-4130479553 2-{2-[3-(1-Methyl-1H-benzimidazol-2-yl)-4-oxo-3,4-dihydroquinazolin-2-yl]ethyl}-1H-isoindole-1,3(2H)-dione Cambridge id 6060000 Oprea1_473931 AC1LRCG6 CHEMBL1533123 ST50255172 BIM-0043015.P001 MLS000109740 2-{2-[3-(1-methylbenzimidazol-2-yl)-4-oxo-3-hydroquinazolin-2-yl]ethyl}benzo[c ]azoline-1,3-dione CBMicro_042896 Oprea1_877404 AKOS000661192 DTXSID30362244 ZINC1211538 [ Show all ]
Inchi Key	AGBKCOAATCRWNI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H19N5O3/c1-29-21-13-7-6-12-20(21)28-26(29)31-22(27-19-11-5-4-10-18(19)25(31)34)14-15-30-23(32)16-8-2-3-9-17(16)24(30)33/h2-13H,14-15H2,1H3
PubChem CID	1366419
ChEMBL	CHEMBL1533123
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4726	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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