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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3978574
Molecular formula	C31H42Cl2N4O2
IUPAC name	3,4-dichloro-N-[[(3R,5R)-3-[2-[(2S)-2-methylpiperidin-1-yl]ethyl]-2-oxo-1-[(2S)-2-phenylbutyl]-1,4-diazepan-5-yl]methyl]benzamide
Molecular weight	573.603
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	6.1
Synonyms	BDBM232092 US9340517, 480
Inchi Key	AGILIWXVJIFSMA-MLUWVZQDSA-N
Inchi ID	InChI=1S/C31H42Cl2N4O2/c1-3-23(24-10-5-4-6-11-24)21-37-17-14-26(20-34-30(38)25-12-13-27(32)28(33)19-25)35-29(31(37)39)15-18-36-16-8-7-9-22(36)2/h4-6,10-13,19,22-23,26,29,35H,3,7-9,14-18,20-21H2,1-2H3,(H,34,38)/t22-,23+,26+,29+/m0/s1
PubChem CID	127054282
ChEMBL	CHEMBL3978574
IUPHAR	N/A
BindingDB	232092
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
533927	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325

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