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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1MFBBP
Molecular formula	C23H27N3O4S
IUPAC name	1-[1-(4-ethoxyphenyl)-2,5-dioxopyrrolidin-3-yl]-3-ethyl-1-[(4-methoxyphenyl)methyl]thiourea
Molecular weight	441.546
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	1-[1-(4-ethoxyphenyl)-2,5-dioxopyrrolidin-3-yl]-3-ethyl-1-[(4-methoxyphenyl)methyl]thiourea N-[1-(4-ethoxyphenyl)-2,5-dioxo-3-pyrrolidinyl]-N'-ethyl-N-(4-methoxybenzyl)thiourea CHEMBL1600398 MLS000577798 Oprea1_064808 HMS2282P07 MolPort-002-168-309 SMR000187183 MCULE-1687560132 [ Show all ]
Inchi Key	AHFRUIGGNIFVPP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H27N3O4S/c1-4-24-23(31)25(15-16-6-10-18(29-3)11-7-16)20-14-21(27)26(22(20)28)17-8-12-19(13-9-17)30-5-2/h6-13,20H,4-5,14-15H2,1-3H3,(H,24,31)
PubChem CID	2869020
ChEMBL	CHEMBL1600398
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5509	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463547	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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