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Ligand

NameCHEMBL209380
Molecular formulaC27H33FN2O
IUPAC name4-(4-fluorophenyl)-8-[1-(3-methylphenyl)cyclohexyl]-2,8-diazaspiro[4.5]decan-1-one
Molecular weight420.572
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP4.9
SynonymsSCHEMBL5562071
BDBM50188845
4-(4-fluoro-phenyl)-8-(1-m-tolyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one
rac-4-(4-fluoro-phenyl)-8-(1-m-tolyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one
Inchi KeyAHHHFIOUWFYJQZ-UHFFFAOYSA-N
Inchi IDInChI=1S/C27H33FN2O/c1-20-6-5-7-22(18-20)27(12-3-2-4-13-27)30-16-14-26(15-17-30)24(19-29-25(26)31)21-8-10-23(28)11-9-21/h5-11,18,24H,2-4,12-17,19H2,1H3,(H,29,31)
PubChem CID11464294
ChEMBLCHEMBL209380
IUPHARN/A
BindingDB50188845
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
5541Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
5540Nociceptin receptorP41146OPRL1Homo sapiens (Human)370

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