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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1MXB69
Molecular formula	C21H15F3N4O5
IUPAC name	2-methoxy-N-[2,4,6-trioxo-1-phenyl-5-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzamide
Molecular weight	460.369
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	1.8
Synonyms	2-methoxy-N-[2,4,6-trioxo-1-phenyl-5-(trifluoromethyl)-2,3,4,5,6,7-hexahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl]benzamide CHEMBL1518693 MolPort-000-762-167 AKOS022010159 NCGC00102268-01 2-methoxy-N-[2,4,6-trioxo-1-phenyl-5-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzamide HMS1806L19 AKOS001719404 MolPort-002-610-024 STL052046 714232-55-0 MCULE-8478594131 AKOS005705160 N-[4-hydroxy-2,6-dioxo-1-phenyl-5-(trifluoromethyl)-2,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-methoxybenzamide [ Show all ]
Inchi Key	AHSAASFIYMEYDM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H15F3N4O5/c1-33-13-10-6-5-9-12(13)16(29)27-20(21(22,23)24)14-15(25-18(20)31)28(19(32)26-17(14)30)11-7-3-2-4-8-11/h2-10H,1H3,(H,25,31)(H,27,29)(H,26,30,32)
PubChem CID	3762857
ChEMBL	CHEMBL1518693
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463585	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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