Home Research Services Publications People Teaching Job Opening Facilities News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR NeBcon WDL-RF ATPbind DockRMSD

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

Ligand

NameCHEMBL347750
Molecular formulaC21H28N2O2
IUPAC name3-(3-hydroxyphenyl)-2,2-dimethyl-3-(methylamino)-N-(3-phenylpropyl)propanamide
Molecular weight340.467
Hydrogen bond acceptor3
Hydrogen bond donor3
XlogP3.5
SynonymsSCHEMBL7101712
BDBM50086366
3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-(3-phenyl-propyl)-propionamide
N-(3-Phenylpropyl)-alpha,alpha-dimethyl-beta-(methylamino)-3-hydroxybenzenepropanamide
Inchi KeyAHTQSMPGKJEFNT-UHFFFAOYSA-N
Inchi IDInChI=1S/C21H28N2O2/c1-21(2,19(22-3)17-12-7-13-18(24)15-17)20(25)23-14-8-11-16-9-5-4-6-10-16/h4-7,9-10,12-13,15,19,22,24H,8,11,14H2,1-3H3,(H,23,25)
PubChem CID17798978
ChEMBLCHEMBL347750
IUPHARN/A
BindingDB50086366
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
5870Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
5872Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
5871Mu-type opioid receptorP33535Oprm1Rattus norvegicus (Rat)398

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218