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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3975079
Molecular formula	C20H23F3N4O4
IUPAC name	5-cyclopropyl-N-[(5-methyl-1,2,4-oxadiazol-3-yl)-(3-methyloxetan-3-yl)methyl]-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxypyridine-2-carboxamide
Molecular weight	440.423
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	3.4
Synonyms	US9409866, 255 BDBM240539 SCHEMBL15776308 5-cyclopropyl-N-[(5-methyl-1,2,4-oxadiazol-3-yl)-(3-methyloxetan-3-yl)methyl]-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxypyridine-2-carboxamide US9409866, 254 AHXHLHDSESGHBO-VQVVDHBBSA-N [ Show all ]
Inchi Key	AHXHLHDSESGHBO-VQVVDHBBSA-N
Inchi ID	InChI=1S/C20H23F3N4O4/c1-10(20(21,22)23)30-15-6-14(24-7-13(15)12-4-5-12)18(28)26-16(19(3)8-29-9-19)17-25-11(2)31-27-17/h6-7,10,12,16H,4-5,8-9H2,1-3H3,(H,26,28)/t10-,16?/m0/s1
PubChem CID	90203659
ChEMBL	CHEMBL3975079
IUPHAR	N/A
BindingDB	240539
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536090	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
536089	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360

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