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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL259479
Molecular formula	C31H33ClN6O4S
IUPAC name	6-[4-[1-[4-(6-chloro-1,3-benzothiazol-2-yl)piperazin-1-yl]-2-methyl-1-oxopropan-2-yl]oxyphenyl]-3-methyl-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Molecular weight	621.153
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.6
Synonyms	BDBM50375415
Inchi Key	AIVHUDXQWUQKOR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H33ClN6O4S/c1-5-12-38-24-18-23(33-26(24)27(39)35(4)30(38)41)19-6-9-21(10-7-19)42-31(2,3)28(40)36-13-15-37(16-14-36)29-34-22-11-8-20(32)17-25(22)43-29/h6-11,17-18,33H,5,12-16H2,1-4H3
PubChem CID	44451166
ChEMBL	CHEMBL259479
IUPHAR	N/A
BindingDB	50375415
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6553	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
6552	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332

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