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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AM 281
Molecular formula	C21H19Cl2IN4O2
IUPAC name	1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholin-4-ylpyrazole-3-carboxamide
Molecular weight	557.213
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.3
Synonyms	RT-011256 ZINC2575699 1-(2,4-DICHLORO-PHENYL)-5-(4-IODO-PHENYL)-4-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID MORPHOLIN-4-YL AMIDE AM281 CHEBI:93039 HMS3267K18 L023967 SR-01000597389 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholin-4-ylpyrazole-3-carboxamide ACM202463681 BC600570 CTK8E9266 NCGC00025009-01 TRA0027415 1H-Pyrazole-3-carboxamide,1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl- BN0064 FT-0752198 J-013143 SBP4A4DYH2 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(morpholin-4-yl)-1H-pyrazole-3-carboxamide AM281, >=98% (HPLC) MFCD01861180 SR-01000597389-1 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholino-1H-pyrazole-3-carboxamide AJFFBPZYXRNAIC-UHFFFAOYSA-N BCP07951 D0UD9H NCGC00025009-02 UNII-SBP4A4DYH2 202463-68-1 AM-281 BRD-K59419204-001-01-9 GTPL741 KB-309876 SCHEMBL1517458 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide AC1N7ICF B6603 CHEMBL476833 MolPort-003-940-033 Tocris-1115 1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl- AKOS024456391 BDBM50267372 EX-A1546 [ Show all ]
Inchi Key	AJFFBPZYXRNAIC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H19Cl2IN4O2/c1-13-19(21(29)26-27-8-10-30-11-9-27)25-28(18-7-4-15(22)12-17(18)23)20(13)14-2-5-16(24)6-3-14/h2-7,12H,8-11H2,1H3,(H,26,29)
PubChem CID	4302962
ChEMBL	CHEMBL476833
IUPHAR	741
BindingDB	50267372
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6855	Cannabinoid receptor 1	P20272	Cnr1	Rattus norvegicus (Rat)	473
6856	Cannabinoid receptor 1	P21554	CNR1	Homo sapiens (Human)	472
6854	Cannabinoid receptor 2	Q9QZN9	Cnr2	Rattus norvegicus (Rat)	360
6858	Cannabinoid receptor 2	P34972	CNR2	Homo sapiens (Human)	360
6857	G-protein coupled receptor 55	Q9Y2T6	GPR55	Homo sapiens (Human)	319

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