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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1684705
Molecular formula	C25H40FN3O3
IUPAC name	cyclopentyl-[(1S,4S)-5-[(1S,3R)-3-[(3-fluorooxan-4-yl)amino]-1-propan-2-ylcyclopentanecarbonyl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]methanone
Molecular weight	449.611
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	BDBM50338134 ((1S,4S)-5-(cyclopentanecarbonyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)((1S,3R)-3-(3-fluorotetrahydro-2H-pyran-4-ylamino)-1-isopropylcyclopentyl)methanone
Inchi Key	AKMCXNQIYOMGQU-ILAYYOKASA-N
Inchi ID	InChI=1S/C25H40FN3O3/c1-16(2)25(9-7-18(12-25)27-22-8-10-32-15-21(22)26)24(31)29-14-19-11-20(29)13-28(19)23(30)17-5-3-4-6-17/h16-22,27H,3-15H2,1-2H3/t18-,19+,20+,21?,22?,25+/m1/s1
PubChem CID	53326901
ChEMBL	CHEMBL1684705
IUPHAR	N/A
BindingDB	50338134
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7678	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374

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