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Ligand

NameCHEMBL469668
Molecular formulaC20H29F3N2O2
IUPAC name1-[(1S)-2-(4-methylpiperazin-1-yl)-1-[3-(trifluoromethoxy)phenyl]ethyl]cyclohexan-1-ol
Molecular weight386.459
Hydrogen bond acceptor7
Hydrogen bond donor1
XlogP3.9
SynonymsCHEMBL599411
SCHEMBL4625301
BDBM50242927
(-)-1-{(1S)-2-(4-Methylpiperazin-1-yl)-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrocholoride
Inchi KeyAKRIZMRTOCYSRB-GOSISDBHSA-N
Inchi IDInChI=1S/C20H29F3N2O2/c1-24-10-12-25(13-11-24)15-18(19(26)8-3-2-4-9-19)16-6-5-7-17(14-16)27-20(21,22)23/h5-7,14,18,26H,2-4,8-13,15H2,1H3/t18-/m1/s1
PubChem CID11574574
ChEMBLN/A
IUPHARN/A
BindingDB50242927
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
78275-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
78225-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
78265-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
78245-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
78235-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
78255-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479

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