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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000083032
Molecular formula	C16H12Cl2N6S
IUPAC name	6-(3,4-dichlorophenyl)-3-(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
Molecular weight	391.274
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.9
Synonyms	AKOS032394257 ZINC5075220 6-(3,4-dichlorophenyl)-3-(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine MolPort-002-636-377 AC1LDEU8 HMS2384F15 SMR000047142 BDBM42473 MLS002583900 6-(3,4-dichlorophenyl)-3-(2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine CHEMBL1527817 REGID_for_CID_665910 AKOS005695188 MCULE-4208521268 STL041638 BDBM50189922 MolPort-000-767-282 877622-96-3 cid_665910 SCHEMBL17927738 [ Show all ]
Inchi Key	AKVGDCSDHQWUBP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H12Cl2N6S/c17-10-5-4-8(6-11(10)18)13-7-25-16-22-21-15(24(16)23-13)14-9-2-1-3-12(9)19-20-14/h4-6H,1-3,7H2,(H,19,20)
PubChem CID	665910
ChEMBL	CHEMBL1527817
IUPHAR	N/A
BindingDB	42473
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7933	Neuropeptide Y receptor type 1	P25929	NPY1R	Homo sapiens (Human)	384
7932	Neuropeptide Y receptor type 2	P49146	NPY2R	Homo sapiens (Human)	381
7931	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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