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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	VU0405623-1
Molecular formula	C20H11Cl2N3O3
IUPAC name	N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide
Molecular weight	412.226
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.8
Synonyms	N-[3-chloro-4-(4-chloro-1,3-dioxo-2-isoindolyl)phenyl]-2-pyridinecarboxamide N-[3-chloranyl-4-[4-chloranyl-1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]pyridine-2-carboxamide N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide CHEMBL1698378 N-[3-chloro-4-(4-chloro-1,3-diketo-isoindolin-2-yl)phenyl]picolinamide BDBM55087 cid_46869944 [ Show all ]
Inchi Key	ALIHXEMWTHYKGH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H11Cl2N3O3/c21-13-5-3-4-12-17(13)20(28)25(19(12)27)16-8-7-11(10-14(16)22)24-18(26)15-6-1-2-9-23-15/h1-10H,(H,24,26)
PubChem CID	46869944
ChEMBL	CHEMBL1698378
IUPHAR	N/A
BindingDB	55087
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8296	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
8297	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912

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