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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2057760
Molecular formula	C34H39FN4O2
IUPAC name	N-[(1R,5R)-8-[(6-fluoronaphthalen-2-yl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]-4-(1-phenylcyclopropanecarbonyl)-1,4-diazepane-1-carboxamide
Molecular weight	554.71
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50387658 SCHEMBL18841106
Inchi Key	ALNPYJIMVMNPSZ-FIRIVFDPSA-N
Inchi ID	InChI=1S/C34H39FN4O2/c35-28-10-9-25-19-24(7-8-26(25)20-28)23-39-30-11-12-31(39)22-29(21-30)36-33(41)38-16-4-15-37(17-18-38)32(40)34(13-14-34)27-5-2-1-3-6-27/h1-3,5-10,19-20,29-31H,4,11-18,21-23H2,(H,36,41)/t30-,31-/m1/s1
PubChem CID	70692666
ChEMBL	CHEMBL2057760
IUPHAR	N/A
BindingDB	50387658
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8435	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355

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