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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL567246
Molecular formula	C24H28ClN5O3
IUPAC name	1-(4-chlorophenyl)-3-[4-[2-(4-hydroxypiperidin-1-yl)ethoxy]-3-(2-methylpyrazol-3-yl)phenyl]urea
Molecular weight	469.97
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.0
Synonyms	BDBM50301480 SCHEMBL1165695 1-(4-chlorophenyl)-3-(4-(2-(4-hydroxypiperidin-1-yl)ethoxy)-3-(1-methyl-1H-pyrazol-5-yl)phenyl)urea
Inchi Key	AMNMOWAGJOKXAY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H28ClN5O3/c1-29-22(8-11-26-29)21-16-19(28-24(32)27-18-4-2-17(25)3-5-18)6-7-23(21)33-15-14-30-12-9-20(31)10-13-30/h2-8,11,16,20,31H,9-10,12-15H2,1H3,(H2,27,28,32)
PubChem CID	45486710
ChEMBL	CHEMBL567246
IUPHAR	N/A
BindingDB	50301480
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9077	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
9078	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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