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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL1603509
Molecular formula	C26H26F6N2O2
IUPAC name	N-[3,5-bis(trifluoromethyl)phenyl]-3-cyclopentyl-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide
Molecular weight	512.496
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	6.3
Synonyms	AMXIUTIAGYTSCN-UHFFFAOYSA-N 3-cyclopentyl-1-(2,6-dimethylphenyl)-5-oxo-pyrrolidine-3-carboxylic acid (3,5-bis-trifluoromethyl-phenyl)-amide CHEMBL3973803
Inchi Key	AMXIUTIAGYTSCN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H26F6N2O2/c1-15-6-5-7-16(2)22(15)34-14-24(13-21(34)35,17-8-3-4-9-17)23(36)33-20-11-18(25(27,28)29)10-19(12-20)26(30,31)32/h5-7,10-12,17H,3-4,8-9,13-14H2,1-2H3,(H,33,36)
PubChem CID	51033903
ChEMBL	CHEMBL3973803
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536232	Chemokine-like receptor 1	Q99788	CMKLR1	Homo sapiens (Human)	373

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