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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL425594
Molecular formula	C26H27N5O3S
IUPAC name	5-[4-[(4-methylsulfonylphenyl)methylamino]phenyl]-6-(phenylmethoxymethyl)pyrimidine-2,4-diamine
Molecular weight	489.594
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	3.0
Synonyms	BDBM19387 SCHEMBL6363980 6-[(Benzyloxy)methyl]-5-(4-{[4-(methylsulfonyl)benzyl]amino}phenyl)pyrimidine-2,4-diamine 2,4-diaminopyrimidine derivative, 8c AMXPCCCIUNIREO-UHFFFAOYSA-N 6-[(benzyloxy)methyl]-5-(4-{[(4-methanesulfonylphenyl)methyl]amino}phenyl)pyrimidine-2,4-diamine [ Show all ]
Inchi Key	AMXPCCCIUNIREO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27N5O3S/c1-35(32,33)22-13-7-18(8-14-22)15-29-21-11-9-20(10-12-21)24-23(30-26(28)31-25(24)27)17-34-16-19-5-3-2-4-6-19/h2-14,29H,15-17H2,1H3,(H4,27,28,30,31)
PubChem CID	11225576
ChEMBL	CHEMBL425594
IUPHAR	N/A
BindingDB	19387
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9341	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366

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