Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000064011
Molecular formula	C13H10N2O2S2
IUPAC name	N-quinolin-5-ylthiophene-2-sulfonamide
Molecular weight	290.355
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.7
Synonyms	AC1M0RHL N-(5-quinolinyl)-2-thiophenesulfonamide HMS2428G13 AKOS027648697 N-(5-quinolyl)thiophene-2-sulfonamide CHEMBL1343705 SR-01000617010 MLS000057468 BDBM37678 N-quinolin-5-ylthiophene-2-sulfonamide cid_2082094 SR-01000617010-2 [ Show all ]
Inchi Key	ANEULYGKZNTCEI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H10N2O2S2/c16-19(17,13-7-3-9-18-13)15-12-6-1-5-11-10(12)4-2-8-14-11/h1-9,15H
PubChem CID	2082094
ChEMBL	CHEMBL1343705
IUPHAR	N/A
BindingDB	37678
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9494	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
9498	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350
9500	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
9493	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
9496	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
9495	N-formyl peptide receptor 2	P25090	FPR2	Homo sapiens (Human)	351
9499	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
9497	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218