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Ligand

NameGSK163090
Molecular formulaC25H29N5O
IUPAC name1-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]imidazolidin-2-one
Molecular weight415.541
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP3.4
Synonyms844903-58-8
GSK-163090
UNII-7XI927X82B
CHEMBL1631540
7XI927X82B
[ Show all ]
Inchi KeyANGUXJDGJCHGOG-UHFFFAOYSA-N
Inchi IDInChI=1S/C25H29N5O/c1-19-8-9-22-23(27-19)6-3-7-24(22)29-16-14-28(15-17-29)12-10-20-4-2-5-21(18-20)30-13-11-26-25(30)31/h2-9,18H,10-17H2,1H3,(H,26,31)
PubChem CID11292933
ChEMBLCHEMBL1631540
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 12
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
95465-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
95435-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
95455-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
95505-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
95415-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
95495-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
95445-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
95425-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
9547Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
9552Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
9551D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
9548D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400

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