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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000102793
Molecular formula	C20H15N3O4S2
IUPAC name	N-[3-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide
Molecular weight	425.477
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.5
Synonyms	F0695-0087 SMR000018257 BDBM48976 MLS002152835 CHEMBL1423773 N-[3-(2-thiazolo[5,4-b]pyridinyl)phenyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide AC1NSINO HMS2246P03 SR-01000140327 CCG-33288 N-(3-(thiazolo[5,4-b]pyridin-2-yl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonamide cid_5310296 N-[3-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-6-sulfonamide AKOS024679883 SR-01000140327-1 N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl)-2,3-dihydro-1,4-benzodioxin-6-sulfonamide [ Show all ]
Inchi Key	ANNOXMPVMJABQL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H15N3O4S2/c24-29(25,15-6-7-17-18(12-15)27-10-9-26-17)23-14-4-1-3-13(11-14)19-22-16-5-2-8-21-20(16)28-19/h1-8,11-12,23H,9-10H2
PubChem CID	5310296
ChEMBL	CHEMBL1423773
IUPHAR	N/A
BindingDB	48976
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9707	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
9708	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
9706	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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