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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL329693
Molecular formula	C33H31F3N4O5S
IUPAC name	N-[2-[4-[[3-butyl-5-oxo-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phenyl]sulfonyl-3,5-dimethylfuran-2-carboxamide
Molecular weight	652.689
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	7.1
Synonyms	BDBM50039899 N-[(3,5-Dimethyl-2-furanyl)carbonyl]-4'-[[[1-[2-(trifluoromethyl)phenyl]-3-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol]-4-yl]methyl]-1,1'-biphenyl-2-sulfonamide 4''-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5-dihydro-[1,2,4]triazol-4-ylmethyl]-biphenyl-2-sulfonic acid (3,5-dimethyl-furan-2-carbonyl)-amide
Inchi Key	AOOWLKVDPNXOHY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H31F3N4O5S/c1-4-5-14-29-37-40(27-12-8-7-11-26(27)33(34,35)36)32(42)39(29)20-23-15-17-24(18-16-23)25-10-6-9-13-28(25)46(43,44)38-31(41)30-21(2)19-22(3)45-30/h6-13,15-19H,4-5,14,20H2,1-3H3,(H,38,41)
PubChem CID	10326942
ChEMBL	CHEMBL329693
IUPHAR	N/A
BindingDB	50039899
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10455	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
10456	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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