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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3289645
Molecular formula	C19H22F3N3O
IUPAC name	1-pyridin-2-yl-4-[3-[4-(trifluoromethyl)phenoxy]propyl]piperazine
Molecular weight	365.4
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	4.0
Synonyms	BDBM50017965
Inchi Key	APDUBUJHUYQKMX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H22F3N3O/c20-19(21,22)16-5-7-17(8-6-16)26-15-3-10-24-11-13-25(14-12-24)18-4-1-2-9-23-18/h1-2,4-9H,3,10-15H2
PubChem CID	90644057
ChEMBL	CHEMBL3289645
IUPHAR	N/A
BindingDB	50017965
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10873	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
10877	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
10875	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
10874	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
10876	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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