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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL181278
Molecular formula	C27H34N2O5
IUPAC name	2-[2-[4-[1-(2-ethoxyethyl)indol-3-yl]piperidin-1-yl]ethoxy]-4-methoxybenzoic acid
Molecular weight	466.578
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	1.6
Synonyms	2-(2-{4-[1-(2-Ethoxy-ethyl)-1H-indol-3-yl]-piperidin-1-yl}-ethoxy)-4-methoxy-benzoic acid BDBM50156893 2-(2-{4-[1-(2-ethoxyethyl)-1H-indol-3-yl]piperidin-1-yl}ethoxy)-4-methoxybenzoic acid
Inchi Key	APMPCPAXNMGHPX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H34N2O5/c1-3-33-16-15-29-19-24(22-6-4-5-7-25(22)29)20-10-12-28(13-11-20)14-17-34-26-18-21(32-2)8-9-23(26)27(30)31/h4-9,18-20H,3,10-17H2,1-2H3,(H,30,31)
PubChem CID	11340290
ChEMBL	CHEMBL181278
IUPHAR	N/A
BindingDB	50156893
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11133	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
11132	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
11131	Histamine H3 receptor	P58406	Hrh3	Mus musculus (Mouse)	445

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